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Psoriasis Vulgaris clinical trials

View clinical trials related to Psoriasis Vulgaris.

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NCT ID: NCT06064084 Completed - Psoriasis Vulgaris Clinical Trials

Incretin Effect in Patients With Psoriasis and Controls

Start date: September 11, 2011
Phase:
Study type: Observational

To investigate the incretin effect and postprandial incretin responses in plasma in patients with psoriasis

NCT ID: NCT06042647 Completed - Psoriasis Vulgaris Clinical Trials

Anti-Inflammatory Effects of 0.045% Tazarotene/0.01% Halobetasol Lotion in Psoriasis

Start date: July 13, 2023
Phase: Phase 4
Study type: Interventional

The objective of this research is to demonstrate superior anti-inflammatory effects, as demonstrated by a reduction in TNF-a and IL-17A, with tazarotene/halobetasol lotion in patients with mild to moderate plaque type psoriasis as compared to clobetasol propionate 0.05% cream.

NCT ID: NCT06011083 Completed - Psoriasis Vulgaris Clinical Trials

Topical Calcipotriol /Betamethasone Ointment in the Treatment of Plaque Psoriasis

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

comparing the clinical efficacy of topical ointment containing calcipotriol and betamethasone dipropionate used alone with the simultaneous use of fractional carbon dioxide laser and the same topical ointment containing these two ingredients as treatment modalities for plaque psoriasis. Additionally, looking into how both therapy modalities affect individuals with psoriasis in terms of how their quality of life is improved.

NCT ID: NCT05647187 Completed - Psoriasis Vulgaris Clinical Trials

Effect Narrow-Band UVB Radiations

UVB
Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Narrow-band UVR affects Interleukin 17 which has a major role in the pathogenesis of psoriasis Vulgaris. the aim of this study to evaluate the serum levels of Interleukin 17 in psoriatic patients and compare with the levels in healthy controls & evaluate the effect of narrow-band ultraviolet B (NB-UVB) on the serum of Interleukin 17 and the treatment of psoriasis Vulgaris.

NCT ID: NCT05488990 Completed - Psoriasis Vulgaris Clinical Trials

Efficacy and Safety of Novel Formulations of Topical Calcipotriol in Patients With Mild to Moderate Plaque Psoriasis

AKVANO-AKP01
Start date: March 25, 2013
Phase: Phase 1/Phase 2
Study type: Interventional

This was a Phase I, single-center, randomized, controlled trial to evaluate the antipsoriatic efficacy of calcipotriol in novel formulations based on AKVANO technology as compared to marketed calcipotriol products (Daivonex® solution and cream) and to evaluate their cutaneous safety in a psoriasis plaque test

NCT ID: NCT05461456 Completed - Psoriasis Clinical Trials

Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1%

ATOFEX-1
Start date: April 1, 2022
Phase: Phase 1
Study type: Interventional

The investigational lotion is envisaged as an short- and long term "Ease & Prevent" monotherapy for adults and children with mild to moderate eczema. With itch representing the most burdensome symptom in eczema, the main objectives with the lotion is fast and efficient itch relief, high tolerability, and high short- and long term safety. This phase 1 study aims to monitor skin tolerability, and how much of the active compound that is absorbed to the bloodstream.

NCT ID: NCT05184348 Completed - Psoriasis Vulgaris Clinical Trials

Plexin B2 Gene Expression and Polymorphisms in Psoriasis

Start date: September 1, 2021
Phase: Phase 1
Study type: Interventional

Patients will be randomly assigned (1:1:1 ) either to ; NB-UVB photo-therapy alone , Acitretin therapy alone or NB-UVB photo-therapy combined with Acitretin therapy randomization will be done by closed envelopes . investigator will be blinded to study drug assignment , while patients and data interpreter will not be masked to study drug assignment.

NCT ID: NCT05120297 Completed - Psoriasis Vulgaris Clinical Trials

A Phase 3 Study of Efficacy and Safety of AK101 in Subjects With Psoriasis

Start date: November 29, 2021
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, multicentered phase III clinical study to evaluate the efficacy and safety of AK101 in the treatment of subjects with moderate-to-severe plaque psoriasis.

NCT ID: NCT04989296 Completed - Psoriasis Vulgaris Clinical Trials

Informative Value of Determining the Level of NF-κB Translocation in Lymphocyte Populations in Children With Psoriasis

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

This study is the first to quantify the level of NF-kB translocation in lymphocyte populations in children and adolescents with psoriasis of varying severity.

NCT ID: NCT04541329 Completed - Psoriasis Vulgaris Clinical Trials

Predicting Inflammatory Skin Disease Response to IL-23 Blockade

Start date: September 16, 2020
Phase: Phase 4
Study type: Interventional

This study examines the effect of IL-23 blockade with Tildrakizumab on the immune cells of psoriatic skin lesions.