Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine whether Aflibercept (Eylea) is effective in the treatment of choroidal neovascularization and fibrovascular proliferation in patients with pseudoxanthoma elasticum (PXE) in terms of preservation or improvement of visual acuity.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02537054
Study type Interventional
Source University Hospital, Bonn
Contact
Status Completed
Phase Phase 2
Start date September 2015
Completion date July 2, 2018

See also
  Status Clinical Trial Phase
Completed NCT05569252 - A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum Phase 2
Recruiting NCT05662085 - Progression Rate of Pseudoxanthoma Elasticum-associated Choroidal and Retinal Degeneration
Completed NCT03070860 - What's Happen Under the Calcification Process in Pseudoxanthoma Elasticum N/A
Completed NCT01446393 - Functional and Structural Characterization of Arteriopathy in Pseudoxanthoma Elasticum (PXE) N/A
Completed NCT00470977 - Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy Phase 1/Phase 2
Recruiting NCT03758534 - Natural History of GACI With or Without ARHR2 or PXE
Recruiting NCT05734196 - The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency Phase 1
Not yet recruiting NCT06462547 - ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency Phase 2
Recruiting NCT01446380 - Phenotypic Expressions in a French Pseudoxanthoma-Elasticum Cohort N/A
Recruiting NCT03813550 - Intestinal Microbiota and Vitamin K Levels in PXE Patients (IMPROVE Study) N/A
Not yet recruiting NCT03364504 - Biological Collection of Kidney Cells N/A
Active, not recruiting NCT02108392 - Characterization of Pseudoxanthoma Elasticum
Recruiting NCT01731080 - Arterial Wall Calcium Load in Pseudoxanthoma Elasticum N/A
Completed NCT00555113 - Evolution of Visual Impairment During Pseudoxanthoma Elasticum N/A
Completed NCT00341419 - Genetic Analysis of Patients With Pseudoxanthoma Elasticum
Withdrawn NCT04441671 - Oral Pyrophosphate Absorption in PXE Disease Phase 2
Recruiting NCT04868578 - PPI Supplementation to Fight ECtopIc Calcification in PXE N/A
Completed NCT05025722 - Pseudoxanthoma Elasticum (PXE) Natural History Biomarkers in PXE Individuals and Their Biological Non-PXE Siblings
Completed NCT01525875 - Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE) Phase 2
Completed NCT05246189 - Employment of Patients With Pseudoxanthoma Elasticum