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Pseudoxanthoma Elasticum (PXE) Natural History Biomarkers in PXE Individuals and Their Biological Non-PXE Siblings

Pseudoxanthoma Elasticum Clinical Trial

Official title:
An Evaluation of Pseudoxanthoma Elasticum (PXE) Natural History Biomarkers in PXE Individuals and Their Biological Non-PXE Siblings

Clinical Trial Summary

This PXE biomarker study aims to characterize the levels of inorganic pyrophosphate (PPi), pyridoxal 5´-phosphate (PLP), and other biomarkers relevant to PXE and ectopic calcification in both PXE patients and their biological siblings who are PXE carriers or normal non-PXE individuals.

Clinical Trial Description

This non-interventional PXE study is designed to assess differences in circulation levels of selective biomarkers related to PXE and tissue-nonspecific alkaline phosphatase (TNAP) inhibition, between PXE patients, PXE carriers, and non-PXE normal individuals. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05025722
Study type Observational
Source Daiichi Sankyo, Inc.
Contact
Status Completed
Phase
Start date August 30, 2021
Completion date August 11, 2022
View Details
See also
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