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Pseudoexfoliation Syndrome clinical trials

View clinical trials related to Pseudoexfoliation Syndrome.

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NCT ID: NCT06423079 Completed - Clinical trials for Pseudoexfoliation Syndrome

Scleral Fixation for Intraocular Lens-Bag Dislocation

Start date: May 10, 2017
Phase:
Study type: Observational

Novel introflective sutures offer a minimally invasive approach for stable fixation of dislocated bag-IOL complexes, preserving visual acuity and reducing corneal complications in patients with pseudoexfoliation syndrome.

NCT ID: NCT06121154 Completed - Sarcopenia Clinical Trials

Pseudoexfoliation Syndrome, Sarcopenia and Chronic Pain

Start date: March 30, 2023
Phase:
Study type: Observational

Aim: Pseudoexfoliation syndrome (PEX) is a systemic disease of connective tissue, it can also contribute to sarcopenia and chronic musculoskeletal pain with common pathways. 1. First aim of this study was to investigate whether the rate of sarcopenia is higher in patients with PEX 2. Second aim was to investigate the association between PEX, sarcopenia parameters and chronic musculoskeletal pain. Methods: A total of 96-patients were enrolled in this study and divided into two groups: PEX-positive (n=48) and PEX-negative (n=48) patients. The variables: the demographic data, sarcopenia parameters (SARC-F-questionnaire, hand-grip strength, chair-rise test, gait speed) and pain parameters (having any chronic musculoskeletal pain, pain regions and visual analogue scale-pain).

NCT ID: NCT06053554 Recruiting - Clinical trials for Pseudoexfoliation Syndrome

Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome

Start date: September 18, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the surgical outcomes of the two IOL implantation methods for eyes with cataract and PEX in a single-center and with highly experienced surgeons. The goal is to acquire relevant information regarding these two IOL implantation techniques, which will help surgeons to decide which approach to choose, ultimately resulting in a benefit for patients with PEX syndrome who require cataract surgery. The main questions are: Is there a difference in lens tilt and decentration between the both methods. Is there a difference in the frequency and amount of capsular phimosis between the both methods.

NCT ID: NCT05447130 Completed - Clinical trials for Pseudoexfoliation Syndrome

Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.

NCT ID: NCT05156138 Recruiting - Clinical trials for Pseudoexfoliation Syndrome

The Possible Association Between Pseudoexfoliation Syndrome And Corneal Endothelial Cell Changes

Start date: January 24, 2022
Phase:
Study type: Observational

The study aims to compare the endothelial cell count in patients with pseudoexfoliation syndrome to the the endothelial cell count in normal patients above the age of 50.

NCT ID: NCT05113121 Completed - Clinical trials for Pseudoexfoliation Syndrome

Correlation Between Pupil Size and Ocular Signs of Pseudoexfoliation Syndrome

Start date: August 25, 2021
Phase:
Study type: Observational [Patient Registry]

To study possible correlation between the size of the pupil in both room light and after dilation between both eyes in bilateral pseudoexfoliation with Intraocular pressure, lens clarity and stability, Optic disc , Visual changes and glaucoma changes by optical coherence tomography

NCT ID: NCT04590651 Enrolling by invitation - Cataract Clinical Trials

Cataract Surgery in Patients With Pseudoexfoliation and Pseudoexfoliation Glaucoma

PHACOPXG
Start date: September 11, 2020
Phase: N/A
Study type: Interventional

The study aims to document the effect cataract surgery has on the pseudoexfoliation and pseudoexfoliation glaucoma eye. Details such has patient history, history of possible glaucoma, intraocular pressure, status of the eye, operation parameters and postoperative effect will be documented. The study is prospective and randomised . Patients will be divided in to two groups: in one standard phacoemulsification cataract surgery will be preformed. In the second group the anterior chamber angel will be aspirated an extra minute at the end of the case with the IA probe. The aim is to determine weather this extra aspiration will have an effect on postoperative intraocular pressure and other parameters.

NCT ID: NCT04274634 Not yet recruiting - Cataract Clinical Trials

The Oscillation of Crystalline and Intraocular Lenses

Start date: October 2020
Phase:
Study type: Observational

The crystalline lens of the human eye helps to sharpen vision. There can be issues with the support/stability of the lens. This could be seen with the naked eye of an external observer or with the use of a slit lamp. Certain eye conditions can predispose to issues with lens stability. If patients have stability issues with their natural lens- this would be termed as "phakodonesis". However, in patients who have had prior cataract surgery with implantation of an artificial lens (IOL)- this would be termed as "pseudophakodonesis". Eye conditions such as pseudoexfoliation or Marfan-syndrome can lead to unstable lens support- this can be detected if there are advanced stability issues. However, small instability in the eye's would not be detected with present descriptive methods. The authors have designed a high-speed camera which is able to detect stability of the lens, especially during eye movements. The high-speed camera can detect variation in the change of light reflex from the lens and calculate the amount of lens instability/oscillation. The results (in normal eyes) of this high-speed camera has already been published in a peer-review journal. It is non-contact and measures lens movement. The test lasts less than 5 minutes. Further research is required to assess the amount of lens oscillation (wobbling) in different eye populations - patients with previous cataract surgery (an artificial implant is used to replace the lens) or eye conditions (such as pseudoexfoliation, Marfan syndrome). The amount of lens stability has a role in the planning of further intraocular surgery - especially cataract extraction - however, at present, there is no approved quantitative measurement for this. Participants will be recruited through Anglia Ruskin University (educational establishment), local community groups, and through Southend University Hospital eye clinics (NHS organisation). Participants' data will remain anonymous.

NCT ID: NCT03453827 Completed - Cataract Clinical Trials

Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery

Start date: April 1, 2016
Phase: N/A
Study type: Observational

To evaluate long-term intraocular lens (IOL) decentration and tilt in eyes with pseudoexfoliation syndrome (PES) following cataract surgery using Visante anterior segment OCT and iTrace Visual Function Analyzer.

NCT ID: NCT03265457 Not yet recruiting - Clinical trials for Pseudoexfoliation Syndrome

The Endothelial Count in Pxf

Start date: October 1, 2018
Phase:
Study type: Observational

Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.