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Pruritus clinical trials

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NCT ID: NCT01232985 Completed - Atopic Dermatitis Clinical Trials

Efficacy and Tolerability Study of Device, RD047-26 for the Treatment of Mild to Moderate Atopic Dermatitis in Adults

Start date: October 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out if investigational device, RD047-26, is safe and useful for the treatment of mild to moderate atopic dermatitis.

NCT ID: NCT01114672 Completed - Pruritis Clinical Trials

A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patients

CRN11
Start date: July 2010
Phase: Phase 4
Study type: Interventional

Pruritis (itching) is common in many people with chronic renal failure on hemodialysis. There may be many different reasons for the pruritis. Efforts to treat the problem have not been very effective. Vitamin D levels have been found to be low in many hemodialysis patients. Since vitamin D plays an important role in the skin and is effective in treatment of certain skin conditions that involve pruritis, it may have a role in treatment of pruritis in hemodialysis patients. The objective of the investigators study is to determine the effect of supplementation with oral vitamin D2 (ergocalciferol) on pruritis in hemodialysis patients.

NCT ID: NCT01074164 Completed - Atopic Dermatitis Clinical Trials

Acupressure in Pruritus for Atopic Dermatitis

Start date: February 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to see if acupressure will be effective at reducing itch in people with atopic dermatitis (AD).

NCT ID: NCT01071057 Completed - Pruritus Clinical Trials

Naloxone for the Treatment of Opioid-Induced Pruritus

Start date: December 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to improve how we treat itching, a common side effect associated with the use of morphine pain medication. Itching is a problem experienced by up to 30% of the children treated with pain medications in the morphine family. Despite studies demonstrating the effectiveness of using naloxone to treat itchiness in adults receiving morphine pain medications, there are not many studies in children. This study is designed to study how well naloxone works for treatment of itching in children

NCT ID: NCT01055236 Completed - Nausea Clinical Trials

Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients

TAH
Start date: August 2007
Phase: Phase 4
Study type: Interventional

Hydroxyzine is one of antihistamines that antagonizes H1 receptor, and it's effects are reducing pruritus, nausea/vomiting, and the mild effect of sedation.With these effects Hydroxyzine should be used in the prevention of these symptoms.

NCT ID: NCT01033097 Completed - Clinical trials for Pruritus in Patients With Atopic Dermatitis

Safety and Efficacy of DNK333 in Atopic Dermatitis Patients

Start date: November 2009
Phase: Phase 2
Study type: Interventional

This study will assess the safety and efficacy of DNK333 in patients with atopic dermatitis suffering from pruritus, who require systemic treatment of the disease.

NCT ID: NCT00914186 Completed - Atopic Dermatitis Clinical Trials

Study of TS-022 in Adult Patients With Atopic Dermatitis With Pruritus (POC)

Start date: June 2009
Phase: Phase 2
Study type: Interventional

The purpose and (primary) objectives of this study are to evaluate the efficacy, safety, and tolerability of TS-022 in adults with atopic dermatitis who have moderate to very severe pruritus (itching), following a 28-day regimen of twice-daily topical application.

NCT ID: NCT00884325 Completed - Atopic Dermatitis Clinical Trials

Management of Pruritus With Xyzal in Atopic Dermatitis

Start date: February 2009
Phase: Phase 4
Study type: Interventional

It is historically well known that the management of pruritus in atopic dermatitis is very difficult. Most of the patients are not controlled with traditional antihistamines such as Clarinex, Claritin, and Allegra. It will be a welcome addition to our treatment armamentarium if a drug such as Xyzal can control pruritus associated with atopic dermatitis.

NCT ID: NCT00838708 Completed - Clinical trials for Pruritus, Atopic Dermatitis

Phase IIa Safety and Efficacy Study of SRD174 Cream in Patients With AD-associated Pruritus

Start date: January 2009
Phase: Phase 2
Study type: Interventional

Pruritus is an essential feature for the diagnosis of atopic dermatitis and may play an important part in disease progression. Itching has a significant impact on the quality of life of AD sufferers, in particular night-time itching leading to sleep disturbance and subsequent poor daytime performance. The objective of this study is to determine whether SRD174 Cream is a safe and effective therapy for moderate to severe pruritus associated with atopic dermatitis.

NCT ID: NCT00782054 Completed - Pruritus Clinical Trials

Evaluation of Post Burn Rehabilitation Population for Itch Control

Start date: September 2006
Phase: Phase 4
Study type: Interventional

Severe itching following burn injury is a common complication. As many as 87% of burn patients report severe itching. The intense itching can increase anxiety and can interfere with sleep and normal activities of daily living thus affecting quality of life. Often the itching will become so intense patients will scratch or rub the skin until an open wound develops. Current treatment for itching includes antihistamines, steroids. and/or moisturizers, but too often, the patient does not receive relief, even from drugs, and suffers undesirable side effects. Swiss-American Products, Inc, has developed a new skin moisturizer containing a blend of endopeptidase enzymes. These products have resolved itching in other types of skin disease such as dermatitis. The hypothesis that itching can be reduced through the use of these endopeptidase enzyme containing products in the post burn population will be tested.