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Prosthesis Failure clinical trials

View clinical trials related to Prosthesis Failure.

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NCT ID: NCT05508958 Enrolling by invitation - Clinical trials for Loosening, Prosthesis

Cup Revisions Through Anterior or Posterolateral Approach: an RCT

Start date: September 8, 2022
Phase: N/A
Study type: Interventional

With increasing numbers of total hip arthroplasties performed each year, the incidence of problems related to loosening and wear of total hip arthroplasties is expected to also increase. While the anterior approach for primary total hip arthroplasty has demonstrated to result in a faster short-term recovery than the traditional lateral and posterior approach, this effect has not yet been investigated in revision surgery. Accelerating functional outcome may increase patient satisfaction and reduce healthcare costs. The primary objective is to assess whether isolated cup revision surgery through the anterior approach results in increased functional status and higher patient satisfaction than through the posterolateral approach. This is a prospective Randomized Controlled Trial (RCT) in which 68 patients will be included (34 per group). Patients will be evaluated preoperatively and 6 weeks, 3 months and 1 year postoperatively. The main endpoints are functional recovery as measured with the 30-sec Chair Stand Test (30s-CST), 40m Fast Paced Walking Test (40m FPWT) and the Stair Climb Test (SCT). Secondary endpoints are Modified Borg scale outcomes after the functional tests, Numeric Rating Scale (NRS) for pain (rest/movement), Oxford Hip Score (OHS), HOOS-PS, EQ-5D-5L, satisfaction, cup inclination and complications at 30 days and 90 days postoperatively.

NCT ID: NCT05459233 Recruiting - Clinical trials for Aortic Valve Stenosis

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

ECHOCATH
Start date: January 11, 2023
Phase: N/A
Study type: Interventional

Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between echocardiography and catheterization, with an overestimation of the real gradient with echo (vs. cath) in most cases. Thus, the incidence of procedural-device failure may be lower than that reported in the ViV-TAVR literature,

NCT ID: NCT05321589 Completed - Clinical trials for Prosthesis Durability

Accuracy of Conventional and Digital Impression Techniques Used for Maxillary Hybrid Prosthesis

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

evaluation and comparison of the accuracy of conventional and digital impression for full arch screw retained prosthesis for edentulous maxilla.

NCT ID: NCT05296291 Recruiting - Clinical trials for Dental Prosthesis Failure

RCT: Titanium vs FCZ vs Zirconia Framework

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

In recent years, zirconia-based implant-supported bridge designs have begun to be used more and more as an alternative to metal ceramic bridges. Another new material that has been introduced in the clinic is the high translucent monolithic zirconia, which has only been investigated a few follow-up studies with short follow up duration. The aim being to evaluate the clinical outcome of implant-anchored posterior bridges, made from 1. high-translucent monolithic zirconia, 2. zirconia ceramic with porcelain and 3. metal ceramics. The hypothesis is that high-translucent monolithic zirconia has lower rate of complications since surface porcelain veneering is not required. A total of 60 research subjects will be included in the study. Patients in need of a permanent implant-supported bridge, located posterior of the canine in the upper or lower jaw will be asked for participation. Each subject will be treated according to standard treatment protocols with implants from Nobel Biocare, the Branemark implant system and then be randomly assigned to obtain one of the following three type of bridges. 20 research subjects will be included in each of the three study arms. The prosthetic treatment will be carried out according to standard clinic protocol. All research subjects will be evaluated after 1, 3, 5 years. X-rays and photos will be taken at the installation of the bridges and after 1 and 5 years of follow-up or more frequent, depending on individual indication of the patient and the associated standard clinical care protocol. Personal data, implant survival, marginal bone loss and biological and technical complications related to the implants will be recorded. Survival of the bridge, technical and biological complication related to the bridge will also be recorded

NCT ID: NCT05290766 Completed - Clinical trials for Prosthesis Durability

Two Versus Four Implant-supported Fixed Full-arch Prosthesis

Start date: January 4, 2020
Phase: N/A
Study type: Interventional

The aim of this study will be the evaluation of patient satisfaction and oral health-related-quality of life (OHRQoL) of two versus four implants supporting fixed full-arch screw-retained metal acrylic hybrid mandibular prosthesis.

NCT ID: NCT05289752 Completed - Clinical trials for Prosthesis Durability

Direct Versus Indirect Pick up of the Locator Retentive Caps:(Within-patient Study)

Start date: August 30, 2021
Phase: N/A
Study type: Interventional

The purpose of this study will be to evaluate the effect of direct and indirect pick up of the locator retentive caps and compare the clinical results with those of the manufacturer retentive force.

NCT ID: NCT05261204 Active, not recruiting - Prosthesis Survival Clinical Trials

Transcatheter Aortic Valve Implantation Versus Standard Surgical Aortic Valve Operation

TAVISAR
Start date: May 19, 2022
Phase:
Study type: Observational

The mechanical intervention is treating aortic valve stenosis (AVS) which may be performed using the standard open surgical approach for aortic valve replacement (AVR) or transcatheter aortic valve implantation (TAVI). The key question of this study is to establish the difference in all-cause and cause-specific (cardiac vs noncardiac) mortality, all hospitalizations for heart failure within 24 months of follow-up, left ventricular reverse remodeling after adjustment for death, as assessed by means of the left ventricular end-diastolic volume (LVEDV), in patients who received the TAVI vs the standard surgical procedure for AVS.

NCT ID: NCT05220553 Recruiting - Amputation Clinical Trials

A Sensorimotor Prosthesis for the Upper Limb

PROLIMB
Start date: July 10, 2023
Phase: N/A
Study type: Interventional

The finger and fingertip are the most frequently amputated body parts, due to work-related incidents. Yet because of space, weight and cost constraints, prosthetic fingers and fingertips are heavy and bulky with limited active motion and sensation. Most are basic variations on the hook and claw. Lower limb prostheses have become extremely technologically advanced in their design and materials, and upper limbs lag behind in all of these areas. This is due to the complexity of the anatomy and function of the upper limb compared to the lower. There are no commercially available prostheses that offers direct sensory feedback and as such, rely on visual feedback from the wearer. The original PROLIMB study (PROLIMB I) used a Leap Motion Controller (LMC) to investigate the type of grasp adaptation that have been undertaken by patients during the rehabilitation process following amputation and compared this to similar data from healthy volunteers. PROLIMB I also looked at refining the tactile feedback system by investigating the sensation felt on amputation sites in order to feed this information into the haptic feedback system. The vision of the PROLIMB II project is to build on the work completed in PROLIMB I and develop and combine mechanistic models of hand motion and haptic sensing to deliver novel, affordable body-powered prosthetic fingertip digits with enhanced motion and sensation to address current clinical needs and support the quality of life of amputees. With collaboration from the University of Warwick (UoW) and University College London (UCL), Steeper Group and Naked Prosthetics the PROLIMB II study will aim to model, design, fabricate and validate a body-powered prosthetic fingertip digit with integrated sensory feedback. The University Hospital Coventry & Warwickshire (UHCW) will provide the clinical facility with which to assess the comfort, usability and acceptance of this prosthetic in the daily lives of patients with digit amputations. This project will be a proof of concept study with verification of the prosthetic in motion capture (gait) laboratories as well as the use of simple validation data collection over a longer period.

NCT ID: NCT05204797 Recruiting - Clinical trials for Loosening, Prosthesis

Efficacy of Robot-assisted Technique vs Conventional Technique in Preventing Early Micromobilisation After UKA

Start date: October 7, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the percentage of early micromibilisation in unicompartmental knee arthroplasties in robot-assisted technique vs standard technique.

NCT ID: NCT05113303 Active, not recruiting - Knee Osteoarthritis Clinical Trials

COREV 2.0 PMCF-Study on Manual and Navigated Revision Knee Patients

COREV
Start date: March 16, 2022
Phase:
Study type: Observational

The Columbus® Revision endoprosthetic system is bearing the CE-mark. This means that within the scope of this observational study the patient will not be subjected to any additional stressful, study-related medical examinations or treatment measures. The treatment will be carried out exclusively according to medical standards. The study therefore only serves the purpose of observing this standard-compliant treatment and specifically documenting it scientifically.