Effect of Intravenous Magnesium During Robot Assisted Prostatectomy

Prostatic Neoplasms Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02833038
• Other study ID #: AJIRB-MED-CT4-16-074
• Status: Completed
• Phase: N/A
• Start date: April 2016
• Est. completion date: April 2019

Study information

• Verified date: April 2019
• Source: Ajou University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The primary purpose of this study is to investigate the effect of intravenous magnesium on blood pressure after Trendelenburg position during robot assisted prostatectomy.

The secondary purpose of this study is to investigate the effect of intravenous magnesium on pain after robot assisted prostatectomy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: April 2019
• Est. primary completion date: April 2019
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 60 Years to 85 Years

Eligibility

Inclusion Criteria:

• Robot assisted prostatectomy

Exclusion Criteria:

• Allergy to magnesium

• Chronic pain

• Chronic opioid use

• Chronic NSAID use

• Renal dysfunction

• Liver dysfunction

• Cardiac arrythmia

• Seizure

Related Conditions & MeSH terms

• Prostatic Neoplasms

Intervention

Drug:
• Magnesium Sulfate
adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h
• Normal saline
the same bolus and infusion volumes of normal saline

Locations

Country	Name	City	State
Korea, Republic of	Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine	Suwon	Seoum

Sponsors (1)

Lead Sponsor	Collaborator
Ajou University School of Medicine

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mean blood pressure		Up to 2 hours after Trendelenburg position
Secondary	Postoperative pain	pain assessment using visual analog scale	Up to 24 hours after surgery end