Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate a short course (five radiation treatments) of very focused ("stereotactic") external beam radiation therapy for the treatment of early stage prostate cancer.

Clinical Trial Description

External beam radiation therapy for prostate cancer, while effective, takes up to 9 weeks to deliver on a Monday through Friday basis. Recent phase I/II studies from Seattle and Palo Alto using stereotactic guidance to deliver high doses of radiation to the prostate over a 1 to 2 week period of time suggest that outcomes may be equal or superior to standard approaches. These data, combined with markedly improved convenience for patients, make radiosurgery (SBRT) for early-stage prostate cancer an enticing option. The goal of this study is to offer a radiosurgical option to patients within the Sharp system under the umbrella of an IRB-approved study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01540994
Study type	Interventional
Source	Sharp HealthCare
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	January 2011
Completion date	April 5, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03982095` - Survey on Lifestyle, Perceived Barriers and Development of Change in Patients With Prostate Cancer
Recruiting	`NCT05667636` - Early Salvage Stereotactic Radiotherapy for Biochemical Failure After RP	Phase 2
Terminated	`NCT01996696` - Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate	Phase 2
Completed	`NCT01431391` - Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate Cancer	Phase 2
Completed	`NCT03289130` - Dietary Factors and Racial Disparities in Prostate Cancer Aggressiveness
Recruiting	`NCT04462926` - Evaluation of Diagnostic Accuracy of [68Ga]Ga-PSMA-11 PET/CT in Primary Staging of Intermediate and High Risk Prostatic Cancer in Men Newly Diagnosed	N/A
Completed	`NCT00001446` - A Randomized Phase II Study of Oral Thalidomide in Patients With Hormone-Refractory Prostate Cancer	Phase 2
Completed	`NCT02729103` - Treatment Patterns in Metastatic Prostate Cancer	N/A
Completed	`NCT00956228` - Study of Radioimmunoguided Intensity Modulated Radiotherapy (IMRT) for Prostate Cancer	Phase 1/Phase 2
Completed	`NCT00126854` - High Field Magnetic Resonance Spectroscopy Imaging for Follow Up of Prostate Cancer Post Brachytherapy Implantation	N/A
Completed	`NCT00247312` - Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A Prospective Randomized Trial	Phase 3
Completed	`NCT00174863` - Evaluation of SR 31747A Versus Placebo in Androgen-Independent Non Metastatic Prostate Cancer	Phase 2
Terminated	`NCT04221828` - Trial of NanoPac Focal Therapy for Prostate Cancer	Phase 2
Completed	`NCT00001266` - A Phase II Trial of Leuprolide + Flutamide + Suramin in Untreated Poor Prognosis Prostate Carcinoma	Phase 2
Active, not recruiting	`NCT03935282` - Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors	N/A
Completed	`NCT03693742` - MSG Use With 18F-DCFPyL PET/CT Imaging	N/A
Recruiting	`NCT06236789` - Observation Study to Evaluate the Efficacy and Safety of Ifosfamide/Mesna in Patients With Metastatic Castration-resistant Prostate Cancer
Completed	`NCT02977143` - Positive End-expiratory Pressure-induced Increase in Central Venous Pressure as a Predictor of Fluid Responsiveness in Robot-assisted Laparoscopic Surgery	N/A
Completed	`NCT02966535` - The Effect of Prolonged Inspiratory Time on Gas Exchange During Robot-assisted Laparoscopic Surgery With Steep Trendelenburg Position : A Crossover Randomized Clinical Trial	N/A
Completed	`NCT00252460` - CT/MRI Co-registration Prostate Cancer	Phase 1