Role of Soy Supplementation in Prostate Cancer Development

Status Completed

Clinical Trial Summary

This is a randomized study evaluating the effectiveness and direct effect a commercial soy supplement has on prostate cancer and normal prostate tissue. Patient will be randomized it either receive placebo or a commercial soy supplement for 2-4 weeks prior to the planned surgery for treatment of their prostate cancer. Patient's blood and prostate tissue will be evaluated to determine the effects of the soy supplement on the prostate tissue.

Clinical Trial Description

This is a randomized study evaluating the effectiveness and direct effect a commercial soy supplement has on prostate cancer and normal prostate tissue. Patients will be randomized to either receive placebo or a commercial soy supplement for 2-4 weeks prior to the planned surgery for treatment of their prostate cancer. The specific objectives are:

1. To assess the effect of soy supplementation on endogenous hormone production levels and serum prostate specific antigens.

2. To assess the impact of soy supplementation on estrogen receptor expression(ER).

3. To determine the impact of soy isoflavones on cell cycle regulation and associated gene expression. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00255125
Study type	Interventional
Source	VA Office of Research and Development
Contact
Status	Completed
Phase	Phase 3
Start date	September 2005
Completion date	October 2009

View Details

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