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Prostate Hyperplasia clinical trials

View clinical trials related to Prostate Hyperplasia.

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NCT ID: NCT06224218 Recruiting - Clinical trials for Prostate Hyperplasia

Prostate Single Port & Laser Enucleation Comparison Trial

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

Surgical treatments for benign prostatic hyperplasia (BPH) are necessary when non-procedural approaches fail to alleviate lower urinary tract symptoms (LUTS) or bladder outlet obstruction (BOO). Open simple prostatectomy and laser enucleation are recommended for prostatic adenoma size greater than 80 ml. Minimally invasive approaches, such as robotic-assisted simple prostatectomy, have gained popularity due to their comparable outcomes with lower morbidity. The introduction of the da Vinci single-port (SP) robotic platform offers potential advantages, but its outcomes have not been thoroughly investigated. This randomized controlled trial aims to compare the outcomes of SP simple prostatectomy performed using the da Vinci robotic platform versus thulium laser enucleation of the prostate for the treatment of BPH and BOO.

NCT ID: NCT06116851 Recruiting - Prostate Cancer Clinical Trials

Prostate Metabolism, Cancer Risk and Gut Microbiota

PROMIC
Start date: June 1, 2022
Phase:
Study type: Observational

This is a prospective, single center translational multiple cohort study to investigate the association of gut microbiota and prostate cancer.

NCT ID: NCT06038890 Recruiting - Clinical trials for Prostate Hyperplasia

The Learning Curve of Transurethral Holmium Laser Enucleation of the Prostate, Prospective Assessment

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Despite the high-quality evidence supporting the safety and efficacy of Holmium laser enucleation of the prostate (HOLEP), wide adoption of the procedure is hindered by learning difficulties. Veil-sparing HOLEP was popularized with a standardized approach to learning. Prospective multicenter assessment of the learning curve of HoLEP through a novel technique with structured learning protocol. Learning outcome measures will be assessed against time and number of performed cases of new learners in a multicenter study.

NCT ID: NCT05531240 Recruiting - Clinical trials for Prostate Hyperplasia

Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE)

Start date: October 2022
Phase: N/A
Study type: Interventional

This study focuses on the treatment of benign prostatic hyperplasia which causes lower urinary tract symptoms. The purpose of the research project is to evaluate PAE in terms of both medical and health economic outcomes. To evaluate whether there are any differences in effect (IPSS), complications, costs and perceived quality of life compared with TUR-P.

NCT ID: NCT05443451 Recruiting - Clinical trials for Prostate Hyperplasia

BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY

Start date: September 8, 2022
Phase: N/A
Study type: Interventional

This is a pilot study on applying 3D-Ultrasound-Guided Transperineal Microwave needle ablation for men with symptomatic benign prostatic hyperplasia (BPH).

NCT ID: NCT05440981 Recruiting - Clinical trials for Prostate Hyperplasia

Implanted Nitinol Device (iTind) System in Chinese Males With Lower Urinary Tract Symptom Secondary to BPH

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This is a prospective series of consecutive cases of patients undergoing iTind for the treatment of male LUTS.

NCT ID: NCT05023824 Recruiting - Clinical trials for Prostatic Hyperplasia

Efficacy of α-blocker or 5-ARI Withdrawal to Continued Combination Therapy on the Maintenance of LUTS in Men With BPH

Start date: December 8, 2020
Phase: Phase 3
Study type: Interventional

The investigators compare the efficacy of alpha-blocker and 5-ARI withdrawal to continued combination therapy on the maintenance of LUTS and improvement of quality of life outcomes in men with benign prostatic hyperplasia.

NCT ID: NCT04288427 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

Start date: September 25, 2020
Phase: N/A
Study type: Interventional

The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride. The hope is to find ways to predict which patients will not respond to Finasteride so that, in the future, these patients can be identified prior to offering this treatment and they can be offered alternative treatment strategies in its place. The aim is to see if noninvasive techniques such as MRI can detect inflammation of the prostate to assist with early detection of those who will and who will not respond to Finasteride.

NCT ID: NCT03966950 Recruiting - Clinical trials for Postoperative Complications

Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

This study aims to evaluate the possible effect of melatonin on prevention of cognitive dysfunction in the postoperative period of elderly patients undergoing transurethral resection of the prostate (TURP) under spinal anesthesia

NCT ID: NCT03176017 Recruiting - Clinical trials for Prostate Hyperplasia

Ejaculatory Sparing Transurethral Incision Of The Prostate (ES-TUIP) Versus Conventional TUIP

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

In this study, Investigators planned to compare ejaculatory sparing and non-ejaculatory sparing (conventional) TUIP using both subjective and objective assessment tools for the degree of deobstruction. Furthermore, the impact of both techniques on ejaculation and its secondary effect on orgasm perception and different domains of sexual function will be thoroughly assessed.