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Prolapse clinical trials

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NCT ID: NCT06341166 Recruiting - Clinical trials for Mitral Valve Prolapse

Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse

SCIMITAR
Start date: June 19, 2023
Phase:
Study type: Observational

This is a multicenter, observational prospective and retrospective study which aims are: 1) to compute a scoring model potentially predictive for the diagnosis of fibrosis by CMR in patients with MVP; 2) to identify specific features that may predispose to ≥ mild VAs or SCD in patients with MVP.

NCT ID: NCT06341088 Recruiting - Clinical trials for Pelvic Organ Prolapse

Evaluation of Anatomical Results and Sexual Functions After Unilateral and Bilateral Laparoscopic Suture Sacro-hysteropexy Operations

Start date: April 5, 2024
Phase: N/A
Study type: Interventional

The study was planned as prospective and randomized. For the study, patients will be randomized into two groups as unilateral and bilateral suture sacro-hysteropexy operations.

NCT ID: NCT06338852 Completed - Genital Prolapse Clinical Trials

Awareness of Gynaecologists About Role of Physical Therapy in Genital Prolapse

Start date: March 3, 2023
Phase:
Study type: Observational

The aim of this study will be to detect if there is awareness of gynecologists about the role of physical therapy in genital prolapse. Physical therapy plays an important role in assessment, prevention and treatment of pelvic floor dysfunction and genital prolapse, it helps to stimulate and strength pelvic floor muscle. Physical therapy treatments for the pelvic floor may include bladder training, pelvic floor muscles training with or without biofeedback, vaginal cones, electro stimulation or other adjuncts to training.

NCT ID: NCT06330857 Active, not recruiting - Fecal Incontinence Clinical Trials

Recurrence and Bowel Function After Laparoscopic Vaginorectopexy, a Modified Anterior Rectopexy

Start date: May 28, 2002
Phase: N/A
Study type: Interventional

Several pelvic prolapses can render defecation difficulties and they are often treated with different surgical techniques. This study will evaluate a novel variation of a laparoscopic technique used to treat rectal prolapse that is modified to treat multiple pelvic prolapses. 25 women with symptoms of obstructed defecation and multiple pelvic prolapses are assessed before and after surgery with clinical examination, defecography and a questionnaire for bowel function and quality of life. Follow up was scheduled after three and twelve months and at long term (minimum ten years).

NCT ID: NCT06309693 Not yet recruiting - Clinical trials for Pelvic Organ Prolapse

Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy

Start date: July 2024
Phase: N/A
Study type: Interventional

In the effort to reduce postoperative opioid use, there has been increasing interest in developing multimodal pain regimens to better manage postoperative pain while minimizing opioid use and their subsequent side effects that can be detrimental to the healing process. Standard of care approaches to better manage postoperative pain include the Enhanced Recovery After Surgery (ERAS) protocol and the use of peripheral and truncal nerve blocks. Truncal nerve blocks are widely used as an additional modality to provide longer lasting postoperative analgesia and have been adopted as part of the standard of care. The goal of this clinical trial is to compare the effects of ERAS alone versus the quadratus lumborum (QL) nerve block on the postoperative pain experience for women with pelvic organ prolapse undergoing robotic assisted sacrocolpopexy. Subjects will be randomized to the ERAS protocol or the QL block. The main questions the study aims to answer are: 1) does the QL block decrease patient reported pain scores postoperatively; and 2) does the QL block decrease the amount of opioid pain medications in the immediate postoperative period? The primary outcome measure will be median patient reported pain score in the post-anesthesia care unit (PACU) following surgery.

NCT ID: NCT06307873 Recruiting - Clinical trials for Genital Prolapse, Unspecified

Comparison of the Effects of Sacrospinous Fixation and V-notes Lateral Suspension Operations

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Comparison of the effects of sacrospinous fixation and v-notes lateral suspension operations on anatomical recovery, effectiveness and quality of life in a training and research hospital gynecology and obstetrics clinic.

NCT ID: NCT06296316 Recruiting - Genital Prolapse Clinical Trials

Real-Life Use of Transabdominal Restorelle® Meshes in Apical Prolapse Repair

REPAIR
Start date: November 21, 2023
Phase:
Study type: Observational

The purpose of this study is to prospectively follow patients after a sacrocolpopexy with Restorelle® mesh for apical prolapse repair as part of routine care. It will help to describe the safety profile and to confirm the clinical benefits of Restorelle mesh for at least 5 to 8 years post-surgery.

NCT ID: NCT06268782 Completed - Quality of Life Clinical Trials

The Effectiveness of an Online Exercise Program on Well-being of Postpartum Women

Start date: September 21, 2021
Phase: N/A
Study type: Interventional

The aim of this quasi-experimental study was to assess the effectiveness of a 6-week online exercise program on self-assessed quality of life (QoL), physical activity (PA), and dysfunctions of pelvic floor muscles of postpartum women immediately and 6 months after the online intervention. The data were collected with e-questionnaires. The data collection started in September 2021 and ended in September 2023.

NCT ID: NCT06263985 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Axis(TM) Solvent-dehydrate Dermal Allograft in the Treatment of Pelvic Organ Prolapse.

Start date: November 2, 2021
Phase: Phase 4
Study type: Interventional

The goal of this study is to assess improvement in subjects who have undergone Axis Dermis, biologic mesh for pelvic organ prolapse repair. [describe participant population/health conditions]. The main question[s] it aims to answer are: - Is the leading edge of the prolapse above the hymen - Does subject notice a bulge Participants will undergo Axis Dermis pelvic organ prolapse repair procedure.

NCT ID: NCT06260436 Recruiting - Clinical trials for Pelvic Organ Prolapse

Questionnaire of Lower Urinary Tract Symptoms Among Women Before and After Surgical Correction of Uterine Prolapse

Start date: May 30, 2021
Phase:
Study type: Observational

. The study will include patients who underwent Pelvic reconstructive surgery for advanced pelvic organ prolapse (POP-Q ≥ 3). Data regarding preoperative evaluation, surgical procedure, and post-operative management will be collected. women will receive a follow up questionnaire. . The baseline questionnaire included data on age, urinary incontinence, daytime frequency, nocturia, postmicturition dribble, straining, urgency, incomplete bladder emptying, and hesitancy. Women were asked about leakage caused by coughing or sneezing, moving, lifting, sleeping, sexual intercourse, urgency, and rest.