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A Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple Sclerosis

Progressive Multiple Sclerosis Clinical Trial

Official title:
A Randomized, Double-blind, Placebo-controlled Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Subcutaneous Dose of GZ402668 in Men and Women With Progressive Multiple Sclerosis

Clinical Trial Summary

Primary Objective: To assess the safety and tolerability of GZ402668 after a single subcutaneous (SC) dose in men and women with progressive multiple sclerosis. Secondary Objectives: To assess in men and women with progressive multiple sclerosis: - The pharmacokinetic (PK) parameters of GZ402668 after a single SC dose. - The pharmacodynamic (PD) response to GZ402668 after a single SC dose.

Clinical Trial Description

The total study duration from screening for a patient can be approximately up to 8 weeks. Upon completion of this trial, patients treated with GZ402668 will be required to enroll in a 4 year safety follow-up study for continued safety observation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02977533
Study type Interventional
Source Sanofi
Contact
Status Completed
Phase Phase 1
Start date December 1, 2016
Completion date May 16, 2018
View Details
See also
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