Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT05184153 |
Other study ID # |
87RI20_0072 (MEDCCR) |
Secondary ID |
|
Status |
Completed |
Phase |
|
First received |
|
Last updated |
|
Start date |
March 3, 2020 |
Est. completion date |
September 1, 2021 |
Study information
Verified date |
September 2021 |
Source |
University Hospital, Limoges |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
Retrospective cohort of 10 cases of colonic adenocarcinoma of medullary type, operated
between 2000 and 2020 at the University Hospital of Limoges. Collection of relevant data for
this rare entity. Subgroup analysis in search of prognostic factors. Comparison of the data
from our cohort with those from the literature.
Description:
Colorectal cancer (CRC) is the third most common cancer in the world after breast and
prostate cancer (1). It is also the second most common cause of cancer death in France (2).
Most CRCs are adenocarcinomas. However, there is a distinct subtype of adenocarcinoma of
relatively recent recognition, called medullary carcinomas (MC). Its recent recognition as a
distinct entity (3) has made it difficult to study the epidemiologic characteristics of this
cancer, with little population-based data. The largest cohort studied in the literature is
from a US sample of 74 patients seen between 1973 and 2006 (4). The main objective of this
French retrospective study is to highlight some common features in this group of patients
with medullary colorectal cancers, thus improving our knowledge of this cancer subtype and in
particular its prognosis.
Medullary colorectal cancer is a type of cancer with a prognosis of its own, probably
different from the most common histological entity, colorectal adenocarcinoma.
This is a retrospective study a cohort of 10 cases of colonic adenocarcinoma of medullary
type, operated between 2000 and 2020 at the University Hospital of Limoges. A collection of
relevant data was realised for the subgroup analysis in search of prognostic factors for this
rare entity as well as a comparison of the data from this cohort with those from the
literature.