Perioperative Risk Factors of Outcomes for Cardiac Surgery: A Retrospective Study

Prognosis Clinical Trial

Official title:

Perioperative Risk Factors of Outcomes for Cardiac Surgery: A Retrospective Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04980742
• Other study ID #: 2017-111
• Status: Recruiting
• Start date: July 1, 2017
• Est. completion date: December 31, 2021

Study information

• Verified date: August 2020
• Source: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Contact: Min Yan, doctor
• Phone: +86-571-87783716
• Email: zryanmin[@]zju.edu.cn
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Based on a review of about 10,000 patients undergoing cardiac surgery under CPB in West China Hospital of Sichuan University and the Second Affiliated Hospital of Zhejiang University, we try to evalute the effect of blood transfusion on outcomes in cardiac surgery.

Description:

Based on a review of about 10,000 patients undergoing cardiac surgery under CPB in West China Hospital of Sichuan University and the Second Affiliated Hospital of Zhejiang University, the following results were obtained:

1. Perioperative risk factors of death and complications of different organ systems after cardiac surgery, providing evidence for early prevention and intervention;

2. Risk factors of blood transfusion risk were analyzed to provide ideas for reducing intraoperative blood transfusion;

3. The relationship between hemoglobin and complications after heart surgery was explored to provide a factual basis for the development of blood transfusion indications for such patients

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 3000
• Est. completion date: December 31, 2021
• Est. primary completion date: December 31, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• The patients in the west China hospital of sichuan university (July 01, 2011, solstice during June 30, 2017) and the second affiliated hospital of zhejiang university (September 01, 2013, solstice, June 30, 2017) have cardiac surgery under Cardiopulmonary bypass (CPB)

Exclusion Criteria:

• No

Related Conditions & MeSH terms

• Blood Transfusion Complication
• Post-cardiac Surgery
• Prognosis
• Transfusion Reaction

Intervention

Procedure:
• acute normovolemic hemodilution
acute normovolemic hemodilution

Locations

Country	Name	City	State
China	ANH	Hangzhou

Sponsors (1)

Lead Sponsor	Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mortality	all-cause death	28 days after surgery