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Processing, Visual Spatial clinical trials

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NCT ID: NCT05530148 Completed - Cognitive Change Clinical Trials

Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Processing.

MATRICES
Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The investigators' study is designed to test whether prolonged exposure to a martial arts-based intervention (three complex, partner exercises based on Filipino, Chinese and Thai martial arts practices), can improve cognitive processing to a greater degree than resistive exercise of a similar intensity.

NCT ID: NCT04760054 Terminated - Cognitive Change Clinical Trials

Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function

HUBOD
Start date: March 24, 2021
Phase: N/A
Study type: Interventional

The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than aerobic exercise of a similar intensity.

NCT ID: NCT03122288 Completed - Aging Clinical Trials

Individualized Cognitive Training in HIV

TOPS
Start date: July 27, 2017
Phase: N/A
Study type: Interventional

Over 50% of adults with HIV have some form of HIV-Associated Neurocognitive Disorder (HAND) which represents a significant symptom that interferes with everyday functioning and quality of life. As adults age with HIV, they are more likely to develop comorbidities such as cardiovascular disease, hypertension, and insulin resistance which will further contribute to poorer cognitive functioning and HAND. Based upon the Frascati criteria, HAND is diagnosed when a person performs less than 1 to 2 SD below their normative mean (education & age) on measures of two or more cognitive domains (e.g., attention, speed of processing, verbal memory, executive functioning). Yet, from the cognitive literature and prior studies, administering certain computerized cognitive training programs may improve specific cognitive domains in older adults and those with HIV. Such cognitive training programs may be effective in older adults with HIV and therefore investigators may be able to change the diagnosis of HAND in such cognitively vulnerable adults. In this pre-post experimental study, 146 older adults (50+) with HAND will be randomized to be in either: 1) the Individualied-Targeted Cognitive Training, or 2) a no-contact control group. The investigators will focus on those cognitive domains in which participants express an impairment and train them with the corresponding cognitive program. Such an Individualized-Targeted Cognitive Training approach using standard cognitive training programs may offer hope and symptom relief to those individuals diagnosed with HAND. Furthermore, these changes may result in improved everyday functioning (e.g., IADLs) and quality of life. This approach represents a paradigm shift in possibly changing the way HAND is examined. Specific Aim 1: Compare adults who do receive Individualized-Targeted Cognitive Training to those who do not in order to determine whether a change in HAND prevalence and severity occurs between groups. Exploratory Aim 1: Compare adults who do receive individualized-targeted cognitive training to those who do not in order to determine whether this improves everyday functioning (e.g., IADLs). Exploratory Aim 2: Determine whether improvements in HAND and/or everyday functioning over time mediate improvements in quality of life.