Primary Open Angle Glaucoma Clinical Trial
Official title:
Effect of Travoprost 0.004% on Retinal Oximetry in Primary Open Angle Glaucoma
Verified date | October 2012 |
Source | Université de Montréal |
Contact | n/a |
Is FDA regulated | No |
Health authority | Canada: Ethics Review Committee |
Study type | Interventional |
Glaucoma is the second leading cause of blindness among seniors in Canada. It is often
associated with an elevated intraocular pressure (IOP), but its exact mechanism is still
largely unknown. Some studies have shown a link between glaucoma and changes in the amount
of oxygen in the veins of the eye. The study aims to compare the amount of oxygen in ocular
veins among three different groups using a spectrophotometer. This instrument is linked to a
camera and can measure the quantity of oxygen in the veins using different characteristics
of the blood inside.
The groups of the study are: patients without glaucoma, patients suspected of glaucoma and
patients newly diagnosed with glaucoma. The drug the investigators are using, Travoprost
0.004%, will only be administered to the groups suspected or diagnosed with glaucoma.
Travoprost 0.004% is already approved for use in Quebec and is part of standard care. Ten
patients will be recruited into each group for a total of 30 patients in this study. All
patients for the suspected or diagnosed groups will be recruited from the Jewish General
Hospital. Subsequently all testing will be done at the École d'optométrie, Université de
Montréal
Status | Not yet recruiting |
Enrollment | 30 |
Est. completion date | March 2013 |
Est. primary completion date | March 2013 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 45 Years to 80 Years |
Eligibility |
Inclusion Criteria: - good systemic health - irido-corneal angle open - intraocular pressure more than 18 mmHg Exclusion Criteria: - having cardiovascular problem - Hypertension or diabetes - under systemic medication for high blood pressure - had an ocular surgery in the past |
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Canada | University of Montreal | Montreal | Quebec |
Lead Sponsor | Collaborator |
---|---|
Université de Montréal |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Blood oxygenation | For each subject, all the measurements will be done during an 1 hour appointment. | 1 hour | No |
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