Primary Hypertension Clinical Trial
Official title:
Comparison Between Centrally Measured Blood Pressure and Automated Blood Pressure Monitoring for Detection of Early Kidney Dysfunction in Patients With Primary Hypertension
The present study aims to show the difference of blood pressure monitored centrally and automated BP monitoring among patients with primary hypertension for early detection of kidney dysfunction
Hypertension is well known as the silent killer, There is a close relationship between blood
pressure levels and the risk of cardiovascular events, strokes and kidney disease.
Diabetes and hypertension cause up to two-thirds of chronic kidney disease , chronic kidney
disease is a common condition characterized by evidence of kidney damage or dysfunction.
chronic kidney disease is currently classified based on a patient's estimated glomerular
filtration rate and urinary albumin excretion rate , clinicians look for markers of renal
damage (e.g., abnormalities of urinary sediment or organ structure) to diagnose chronic
kidney disease in people with estimated glomerular filtration rate of <60 mL/min/1.73 m2.
Age distribution for hypertension showed progressive rise in blood pressure with increasing
age. Age-related hypertension appears to be predominantly systolic rather than diastolic. The
third NHANES survey reported that the prevalence of hypertension grows significantly with
increasing age in all sex and race groups. In another study, the incidence of hypertension
appeared to increase approximately 5% for each 10-year interval of age Because Central blood
pressure is considered better than peripheral blood pressure in predicting cardiovascular
events, due to wave reflections and viscoelastic properties of the arterial wall Now a day
several non-mercury techniques have been developed during the last ten years in order to
gradually supplant the mercury-auscultatory method, such as the automatic electronic devices
using algorithms based on the oscillometric technique.
Over the last ten years , different protocols are used to validate the accuracy of blood
pressure measuring devices , several automated devices have been successfully validated using
established protocols.
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