Primary Hypertension Clinical Trial
Official title:
National Defense Medical Center
This study aims to investigate the relationship among self-efficacy, anxiety, depressive symptoms, quality of life, lifestyle, heart rate variability and blood pressure control; and to examine the effects of self-titration strategy on self-efficacy, anxiety, depressive symptoms,heart rate variability, sodium excretion, lifestyle modification,quality of life, and blood pressure control in patients with hypertension.
Background: Hypertension is the major cause of mortality for the cardiac, vascular and renal
disease. The effective control of elevated blood pressure may reduce the damages of several
target organs. World Health Organization points out "Innovation and Empowerment for health".
The self-titration strategy may empower patients to self-control their diseases, share
decision-making and increase their ability to self-management their situations and improve
their home blood pressure.
Methods: This experimental study included 222 hypertensive patients from outpatient services
of cardiology departments of a medical center in northern Taiwan. We randomly divided the 72
patients into the experimental group (n=111) and control group (n=111). The experimental
group received self-titration strategy training and lifestyle modification education; the
control group received usual care and lifestyle modification education.
Data were collected for self-efficacy, anxiety symptoms, depressive symptoms, lifestyle and
health-related quality of life using self-report questionnaires. Heart rate variability was
measured with CheckMyHeart device (DailyCare BioMedical, Chungli, Taiwan). Patients evaluated
their home blood pressure by corrected sphygmomanometer. We used the generalized estimating
equation to evaluate the effects of the intervention.
Purpose: Primary outcome to evaluate the effects of self-titration strategy on the
improvement of home blood pressure in patients with hypertension. Secondary outcomes to
evaluate the effects of self-titration strategy on the improvement of self-efficacy, anxiety,
depressive symptoms and lifestyle quality of life in patients with hypertension.
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