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Prevention clinical trials

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NCT ID: NCT01143142 Completed - Prevention Clinical Trials

Vax Facts Human Papillomavirus (HPV): Study of a Computer-based Tailoring System and Mothers' Intentions to Vaccinate Their Daughters Against HPV

Start date: June 2010
Phase: N/A
Study type: Interventional

The goal of this study is to determine whether a two-page print brochure that delivers individually tailored educational messages about the Human papillomavirus (HPV) vaccine increases HPV vaccine-hesitant mothers' intentions to have their adolescent daughters vaccinated against HPV.

NCT ID: NCT01092000 Completed - Prevention Clinical Trials

The Nutrition Challenge: A Health Promotion Campaign

Start date: January 2010
Phase:
Study type: Observational

The purpose of the challenge is to see if we, as the nutrition experts, can follow the dietary and physical activity guidelines promoted to the public. We have an opportunity to "practice what we preach." Scientific evidence demonstrates, knowledge is not enough to change ones'behaviors. It is through positive approaches and lifestyle changes that behavior can be altered. By experiencing the planning, work, and motivation required to make lifestyle changes we can all be better clinicians.

NCT ID: NCT01069939 Completed - Prevention Clinical Trials

Comparative Efficacy & Safety Study of D961H Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With Low-dose Aspirin

Start date: February 2010
Phase: Phase 3
Study type: Interventional

To assess the efficacy of D961H 20 mg once daily (q.d.) versus placebo in continuous treatment involving patients with a history of gastric and/or duodenal ulcers receiving daily Low-dose aspirin therapy by evaluating time from randomisation to occurrence of gastric and/or duodenal ulcers.

NCT ID: NCT01038206 Completed - Substance Use Clinical Trials

Familias Unidas: Preventing Substance Abuse in Hispanic Youth

Start date: August 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The focus of this study will be to test the Familias Unidas Intervention program among Hispanic 8th graders in the Miami-Dade County Public School System. This study will contribute to the advancement of knowledge in both the scientific community and the Hispanic population in Miami-Dade County. It will shed light on whether and to what extent Familias Unidas is effective in preventing drug use and unsafe sexual behavior in Hispanic adolescents. To the scientific community, the investigators will disseminate our findings via peer-reviewed publications and presentations at scientific meetings. The design for the proposed study is a randomized controlled trial. This design is considered the "gold standard" design when evaluating the efficacy of two (or more) treatment conditions. Participants for this study will be 744 Hispanic 8th grade adolescents and their parents recruited from 24 randomly selected middle schools in Miami Dade County that meet the school inclusion/exclusion criteria. A total of 12 schools (for a total of 372 Hispanic adolescents and their parents) will be randomized to Familias Unidas and a total of 12 schools (for a total of 372 Hispanic adolescents and their parents) will be randomized to the Community Practice.

NCT ID: NCT00995462 Completed - Weight Gain Clinical Trials

Prevention of Weight Gain in University Students

PGP2
Start date: September 2006
Phase: N/A
Study type: Interventional

This study assess whether a small-group seminar intervention to prevent weight gain is effective in a general university student population, and to address the relative role of biological vs. lifestyle factors in predicting weight gain in humans.

NCT ID: NCT00981201 Completed - Smoking Clinical Trials

Celecoxib as a Chemopreventive Agent in Current and Former Smokers

Start date: November 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is: - To examine the effect of celecoxib treatment on Ki-67 expression, a marker of cell proliferation, in the bronchial epithelium of current and former smokers. - To examine the toxicity associated with celecoxib administration. - To measure the effect of celecoxib treatment on arachidonic acid metabolites in the bronchial epithelium of current and former smokers.

NCT ID: NCT00966212 Completed - Prevention Clinical Trials

Parent Education for Young Teen Females

Start date: September 2003
Phase: Phase 2/Phase 3
Study type: Interventional

The study has the potential to improve understanding of the link between early alcohol and sexual initiation and to provide a proven, selective, female-focused intervention for addressing these risks. The goal is to set young women on a course that protects their health and reduces the burden that problem drinking and HIV disease is taking on African American and Latino communities.

NCT ID: NCT00891111 Completed - Prevention Clinical Trials

Incentives for Preventative Health Care: Increasing Completion of Health Risk Assessments

Start date: May 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to understand using incentives to encourage employees to increase participation in an aspect of a corporate wellness program - filling out health risk assessments. This study will test whether lottery-linked incentives are more effective than guaranteed incentives in encouraging people to fill out health risk assessments. This study will be run in an employer setting in which rates of health risk assessment completion are suboptimal. This study would be conducted within a workplace setting in which the firm is divided into a number of geographically situated and functionally related subunits. The investigators will run a "complete your health risk assessment now!" program for 4 weeks. Each work unit will obtain a symbol. Every week, one symbol will be randomly drawn, publicly announced, and anyone in that work unit at the firm who has received their preventive screening would receive a $100 prize. In addition, if all of employees in that unit have completed their forms, then the prize will be increased to $125. The investigators expect this condition to result in greater compliance compared to a control condition in which employees would receive weekly reminders and a direct payment of a $25 gift card for completing the form at anytime during the 4 weeks of the study. This is analogous to direct payments that have been used by insurers to encourage completion of such forms in other contexts.

NCT ID: NCT00853463 Completed - Pulmonary Embolism Clinical Trials

Discharge ALERT: Quality Improvement Initiative

Discharge
Start date: April 2009
Phase: N/A
Study type: Interventional

Brigham and Women's Hospital will coordinate a Quality Improvement Initiative at other hospitals that focuses on whether physician notification prior to discharge of high risk VTE patients will reduce the incidence of VTE after hospital discharge.

NCT ID: NCT00839826 Completed - Thromboembolism Clinical Trials

ODiXahip - a Phase IIa Dose Escalating Proof of Principle Trial

ODiXaHip
Start date: December 2002
Phase: Phase 2
Study type: Interventional

Patients undergoing surgery, especially hip and knee surgery, are at high risk for VTE (up to 60 % without prophylaxis). The administration of drugs for thromboprophylaxis, such as heparins, significantly lowers that risk, but heparins have to be applied below the skin (subcutaneously). Additionally, there is a chance of developing a heparin-induced thrombocytopenia (decrease in platelets). Therefore, there is still a need for new agents which are safer and more efficient and which are easier to apply.The purpose of this study is to compare the safety and efficacy of BAY 59-7939 with the safety and efficacy of the licensed drug Enoxaparin. Enoxaparin, a so-called low molecular heparin, is approved and widely used in the area of thromboprophylaxis and will be given once daily subcutaneously.Another important purpose of the study is to find the optimal dose of BAY 59-7939 for thromboprophylaxis after hip replacement surgery. Therefore, there are several dose steps planned.