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Preterm Pregnancy clinical trials

View clinical trials related to Preterm Pregnancy.

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NCT ID: NCT06421506 Not yet recruiting - Clinical trials for Respiratory Distress Syndrome

Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants

Start date: May 2024
Phase: N/A
Study type: Interventional

The aim of this study is to see if giving less invasive surfactant administration (LISA) during high-flow nasal cannula (HFNC) oxygen treatment reduces the need for invasive ventilation in babies with breathing problems born 2-6 weeks early. Less invasive surfactant administration is where surfactant (a naturally produced substance which helps open up the tiny air sacs in the lungs making it easier for babies to breathe) is given into the lungs by putting a small tube into the windpipe through the mouth whilst the baby is awake. The surfactant is given slowly and breathed in. High flow nasal cannula is a form of non-invasive support where a machine delivers warmed, moist oxygen and air through short tubes in the nose. The investigators will be assessing whether a lower percentage of neonates need invasive ventilation within 72 hrs from birth when they have had LISA during HFNC treatment, compared to when they don't receive this treatment. The investigators will also be looking at the length of neonatal unit stay and the cost of the stay. The investigators will also be measuring the lung function of the babies before and after they receive LISA.

NCT ID: NCT06403059 Completed - Preterm Pregnancy Clinical Trials

Cervical Length and Uterocervical Angle as Predictors of Spontaneous Preterm Birth

Start date: October 15, 2023
Phase:
Study type: Observational

This prospective study was carried out on 263 pregnant females aged from 19 to 35 years old carrying singleton, and uncomplicated pregnancy. TVS examination was performed in all cases at 28 and 32 weeks of gestation. The pregnant women recruited in the study closely followed up to delivery. Maternal progesterone was given to all women with short CL (<20mm and more than 10mm) to support pregnancy.

NCT ID: NCT06164080 Completed - Perinatal Problems Clinical Trials

The Effect Of Antenatal Corticosteroids On Early And Late Perinatal Outcomes

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

In this study, the investigators aims to evaluate whether antenatal corticosteroid administration to women likely to give birth in the late preterm period will reduce early and late neonatal complications and contribute to the literature in this sense.

NCT ID: NCT04590677 Recruiting - Preterm Birth Clinical Trials

Prediction of the Onset of Term and Preterm Labour

PREDICT
Start date: October 20, 2020
Phase:
Study type: Observational

This study will collect samples from pregnant women in order to identify biomarkers that relate to onset of spontaneous preterm labour.

NCT ID: NCT03819933 Recruiting - Premature Birth Clinical Trials

Optimizing Family Counseling for Anticipated Extremely Preterm Delivery

Start date: September 17, 2019
Phase: N/A
Study type: Interventional

Antenatal family counseling for anticipated extremely preterm deliveries remains ethically and practically challenging for maternal-fetal medicine specialists and neonatologists alike. The overall goal of this project is to improve antenatal counseling and counseling outcomes for families facing anticipated extremely preterm delivery through innovative, interdisciplinary simulation-based education for maternal fetal medicine specialists and neonatologists, using language preferred by families, and focusing on eliciting values and building partnerships through advanced communication and relational skills.

NCT ID: NCT03504670 Completed - Labor Induction Clinical Trials

Preterm Induction of Labor Timing of Amniotomy: A Randomized Controlled Trial

PITA
Start date: November 14, 2018
Phase: N/A
Study type: Interventional

Artificial rupture of membranes (amniotomy) is a commonly used technique to safely induce and augment labor. It has been shown to reduce the duration of spontaneous and induced labor in term patients (≥37 weeks' gestation). The utility of amniotomy in preterm patients (<37 weeks' gestation) undergoing medically-indicated induction of labor is unknown. However, it remains a commonly used strategy. We will conduct a trial comparing early amniotomy versus late amniotomy during medically-indicated induction of labor between 23.0 and 35.6 weeks gestation. Women will be randomized to early or late amniotomy after the obstetrician has decided to induce labor for a medical indication. We hypothesize that more women in the early amniotomy group will require cesarean delivery, and the duration of labor will increase in the early amniotomy group.