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Preterm Infants clinical trials

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NCT ID: NCT00877175 Completed - Preterm Infants Clinical Trials

Comparison of Instillation and Packing in Mydriasis for Premature Infants

Start date: March 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the mydriatic effect of 2.5% phenylephrine and 1% tropicamide by conventional instillation and lower conjunctival fornix packing in premature infants.

NCT ID: NCT00838474 Completed - Preterm Infants Clinical Trials

The Effect of Music by Mozart on Energy Expenditure in Growing Preterm Infants

Start date: October 2007
Phase: N/A
Study type: Interventional

Music has been consistently shown to reduce stress and increase weight gain in premature infants. The mechanism of this presumed improved metabolic efficiency is unknown. We aim to test the hypothesis that music by Mozart reduces energy expenditure in growing healthy preterm infants.

NCT ID: NCT00838188 Completed - Preterm Infants Clinical Trials

Energy Expenditure in Breast and Bottle Feeding Preterm Infants Fed Their Mother's Breast Milk

Start date: November 2007
Phase: N/A
Study type: Observational

OBJECTIVE. Neonatologists consider early feeding at the breast to be too tiring for preterm infants, although there is no evidence that this is actually the case. It is also not known whether the method of feeding affects energy expenditure. We hypothesized that resting energy expenditure (REE) would be higher after breastfeeding than after bottle feeding. PATIENTS AND METHODS. preterm ( >32 weeks GA) stable infants who are nourished entirely by their mothers' breast milk will be studied when fed expressed breast milk either by bottle or at the breast. REE will be measured for 20 minutes after feeding. Breast milk quantity is evaluated by pre- and post feeding weighing.

NCT ID: NCT00758511 Completed - Preterm Infants Clinical Trials

Pain Reactivity to Non-Pharmacological Interventions Across Repeated Routine Heel-Sticks in Preterm Infants in a Neonatal Intensive Care Unit

PAMINA
Start date: January 2009
Phase: Phase 0
Study type: Interventional

Switzerland is having one of the highest premature rates in Europa and most of the preterm neonates need neonatal intensive care. Up to 80% of the analgesic used in neonatal intensive care units are either "off label used" or "non-licensed" used. As an alternative approach non-pharmacological interventions for pain prevention and relief are increasingly being recommended for the prevention and treatment of mild and moderate pain in this population. This multicenter pilot study will use a randomized three group,repeated measures design. The primary aims of this study of premature neonates are to: 1.) Estimate effect sizes for the impact of the proposed interventions(facilitated tucking alone, sucrose alone and sucrose in combination with tucking)on pain reactivity. 2.) Examine the impact of gestational age on the estimates of efficacy 3.) Examine the impact of the numbers of painful procedures the infant experiences and the concurrent use of analgesic medications on the estimates of efficacy

NCT ID: NCT00707837 Completed - Preterm Infants Clinical Trials

Nutritional Study in Preterm Infants

Start date: May 2005
Phase: Phase 3
Study type: Interventional

An evaluation of a preterm infant formula containing ingredients similar to those found in breastmilk

NCT ID: NCT00611546 Completed - Preterm Infants Clinical Trials

Perenteral Nutrition and Oxidative Stress in Preterm Infants

Start date: April 2003
Phase: N/A
Study type: Interventional

In an effort to decrease the load of peroxides in TPN solutions, multiple studies examined different strategies such as photo-protection, adding multivitamins to the lipid emulsion rather than to the dextrose-amino acid admixture, and adding antioxidants such as glutathione to the TPN solution. However, the role of trace elements as antioxidants, and their interaction with light have not been studied. Also, the impact of TPN-related oxidants on clinical morbidities has not been addressed. Therefore, we aimed in this study of preterm infants to evaluate the role of different components of TPN on urinary peroxides and to examine the biochemical and clinical effects of light protection.

NCT ID: NCT00497289 Completed - Preterm Infants Clinical Trials

Comparison of Two Different Lipid Emulsions for Parenteral Nutrition in Preterm Infants

Start date: January 2006
Phase: Phase 2
Study type: Interventional

The study shall provide evidence for the save and efficient use of a fish oil containing lipid emulsion in parenteral nutrition of preterm infants.Safety will be assessed by monitoring hepatological and hematological laboratory parameters. Efficiency will be assessed by monitoring of inflammatory parameters.

NCT ID: NCT00222456 Completed - Preterm Infants Clinical Trials

Project Early Intervention 2000

Start date: March 1999
Phase: N/A
Study type: Interventional

The purpose of this study is to examine whether an early intervention program may improve cognitive and behavioral short and longterm outcome in preterm infants.