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NCT02662790 Clinical Trial

Dexamethasone on Fetal and Uteroplacental Doppler

Preterm Birth Clinical Trial

Official title:
Effects of Antenatal Dexamethasone Administration on Fetal and Uteroplacental Doppler Waveforms in Women at Risk for Preterm Birth

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02662790
Other study ID # DEXA
Secondary ID
Status Completed
Phase Phase 2
First received January 15, 2016
Last updated January 21, 2016
Start date February 2014
Est. completion date January 2015

Study information
Verified date January 2016
Source Assiut University
Contact n/a
Is FDA regulated No
Health authority Egypt: Institutional Review Board
Study type Interventional

Clinical Trial Summary

The current study aims to investigate the effects of dexamethasone exerted on fetal and uteroplacental circulation as measured by Doppler ultrasonography in pregnancies at risk for preterm birth after 24 hours of its administration.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date January 2015
Est. primary completion date December 2014
Accepts healthy volunteers No
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria:

- Patients at risk of preterm labor to be included were those with preterm uterine contractions, placenta previa, and mild preeclampsia

Exclusion Criteria:

- Patients who were actively in labor, presented with premature rupture of membranes, intrauterine growth restriction (IUGR), those who had received corticosteroids in their pregnancies and/or fetuses with suspected structural abnormalities

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Other:
• Doppler

Locations
Country Name City State
Egypt Ahmed Abbas Assiut Cairo

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary mean of Doppler Resistance index (RI) 24 hours Yes
Secondary mean of Doppler Pulsatility index (PI) 24 hours Yes
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