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Presbyopia clinical trials

View clinical trials related to Presbyopia.

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NCT ID: NCT05624320 Withdrawn - Presbyopia Clinical Trials

Using AGN-190584 in Subjects Utilizing Single -Use Daily, Contact Lenses

Start date: December 1, 2022
Phase: Phase 4
Study type: Interventional

AGN-190584 has gone through many clinical trials showing its safety and effectiveness in individuals from 40-55 years of age. There has been no published data on the use of this product in individuals corrected with contact lenses for distance vision. There are many other applications AGN-190584 could be used for and further studies will show the effectiveness for each.

NCT ID: NCT05393089 Withdrawn - Presbyopia Clinical Trials

Study of AGN-190584 Eye Drops to Assess Safety and Efficacy in Participants Aged 40-80 Years With Pseudophakic Presbyopia

ARIES
Start date: June 9, 2022
Phase: Phase 2
Study type: Interventional

Presbyopia is a condition in which the eye exhibits a diminished ability to focus on near objects with increasing age. This study will assess the safety and exploratory efficacy of AGN-190584 is in treating participants with pseudophakic presbyopia. AGN-190584 is approved (in the United States) for use in adults with presbyopia (including those who are pseudophakic) and this study is being conducted to better understand the safety and efficacy in the pseudophakic presbyopia population. This study is double-masked meaning that neither the participants nor the study doctors will know who will be given AGN-190584 and who will be given vehicle (does not contain treatment drug). Study doctors put the participants in 1 of the 2 groups, called treatment arms. Each group receives a different treatment. There is a 1 in 3 chance that participants will be assigned to vehicle. Approximately 150 participants aged 40-80 years with pseudophakic presbyopia will be enrolled in approximately 30 sites in the US. Participants will receive eye drops of AGN-190584 or vehicle once daily in the morning in each eye for 14 days. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study. The effect of the treatment will be evaluated by medical assessments, checking for side effects and completing questionnaires.

NCT ID: NCT04800016 Withdrawn - Presbyopia Clinical Trials

Real-World Study of Vivity Intraocular Lenses (IOLs)

Start date: June 2021
Phase: N/A
Study type: Interventional

The primary objective of this clinical study is to assess the clinical performance of the AcrySof IQ Vivity Extended Vision IOL in a Chinese population.

NCT ID: NCT04054427 Withdrawn - Cataract Clinical Trials

Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery

Start date: November 2021
Phase: N/A
Study type: Interventional

Controlled, open label, prospective Post Market Clinical Follow-Up, single-center clinical study to investigate visual performance after implantation of a trifocal IOL (PhysIOL Pod L GF) in patients that underwent refractive surgery.

NCT ID: NCT03675438 Withdrawn - Presbyopia Clinical Trials

Safety and Efficacy of a Sub-epitheilal Transformâ„¢ Corneal Allograft (TCA) for Presbyopia Correction

Start date: October 2018
Phase: N/A
Study type: Interventional

The objective of this clinical study is to evaluate the safety and effectiveness of subepithelial implantation of the Allotex TransForm corneal allograft (TCA) for improving near vision in presbyopic subjects.

NCT ID: NCT01059006 Withdrawn - Presbyopia Clinical Trials

Peripheral PresbyLASIK Using the Allegretto Wavelight System For The Treatment of Presbyopia

Start date: January 2010
Phase: N/A
Study type: Interventional

The aim of this study is to analyze the results of PresbyLASIK performed using the wavefront-optimized LASIK for the treatment of presbyopia on low hyperopic and low myopic patients with astigmatism. Visual performance will be assessed using clinical outcome measures of the following: refraction, near, intermediate and distance visual acuity, stereoacuity and contrast sensitivity. Questionnaires will also be used to evaluate how the patient's vision is before and after surgery.

NCT ID: NCT00271661 Withdrawn - Presbyopia Clinical Trials

Presbyopia in Breast Cancer Survivors

Start date: August 2005
Phase: N/A
Study type: Observational

Chemotherapy drugs, used in cancer treatments, may change the timing of a vision condition known as presbyopia. Presbyopia is the inability to focus the eye on close objects, by a process called accommodation. It is caused by an increase in the stiffness of the lens of the eye that occurs naturally with aging. Currently, there are no known treatments that can be used to prevent or delay presbyopia. As a result, the risk, in later life, of having this condition is essentially 100%. The purpose of this research is to determine whether chemotherapy drugs are delaying the age at which people develop symptoms of presbyopia. We hope to establish that presbyopia can in fact be delayed with the use of drugs, which would ultimately lead to further research in this area.