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Premature clinical trials

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NCT ID: NCT04298346 Completed - Premature Clinical Trials

Neurological Fate, Prematurity and Genetic Susceptibility Factors

GENIMOC
Start date: March 9, 2020
Phase:
Study type: Observational

This study could help identify aggravating or protective genetic polymorphisms associated with cerebral palsy. Populations of premature babies at different risk of cerebral palsy could thus be individualized with an impact on their monitoring and on the pathophysiological understanding of the processes leading to neurological lesions.

NCT ID: NCT04283682 Completed - Premature Clinical Trials

Intervention Facilitates Oral Feeding in Premature Infants

Start date: April 8, 2020
Phase: N/A
Study type: Interventional

Skin-to-skin combined with breastfeeding shortened the cycle of full-oral feeding in premature infants

NCT ID: NCT04249193 Completed - Blood Transfusion Clinical Trials

Pulse Oximetry Measurement and Transfusions

POMAT
Start date: April 2014
Phase:
Study type: Observational

The primary purpose of this observational study was to determine if pRBC transfusions decrease the frequency of intermittent hypoxia events in very low birth weight infants (VLBW) during the first six weeks of life. The impact on non-pRBC transfusions on the frequency of intermittent hypoxia was also assessed.

NCT ID: NCT04231799 Completed - Premature Clinical Trials

Delaying First Bathing and Skin Barrier Function on Infant

TEWL
Start date: February 20, 2020
Phase: N/A
Study type: Interventional

It is still unknown when the first bath should be done in premature newborns. Investigators think that delaying the time of the first bath compared to the time in the clinic will show some positive changes in preterm newborns.

NCT ID: NCT04203589 Completed - Cerebral Palsy Clinical Trials

Explorer Babies Early Intervention Program

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Premature babies have a high risk of adverse developmental outcomes. Early intervention approaches are applied to reduce these adverse outcomes or support of developmental delay. Early intervention approaches may vary depending on developmental priorities. While some early intervention methods can consider body structured findings such as posture, tonus, muscle power, others may consider coaching family, enrichment of the environment. The explorer baby program is developed based on the trial and error process. The program tries to find an answer to a unique question: "how trial behavior in infants can be increased and which behaviors of the infants should be supported to increase their trial process?" The Explorer baby program tries to increase exploratory motor behaviors to facilitate development. For this aim, the program tries to explain how a baby learns new skills such as rolling, sitting, babbling, playing peek a boo, etc. in all domains of development while the baby lives in their natural environment. This study aims to investigate the effect of the explorer baby early intervention program.

NCT ID: NCT04168749 Enrolling by invitation - Weight Gain Clinical Trials

Efficacy and Safety of Industrially Prepared 3 Chamber Bag Parenteral Nutrition for Premature Infant

ESIP3CB
Start date: November 15, 2019
Phase:
Study type: Observational

This study was designed to evaluate whether industrially prepared standardizing total parenteral nutrition is at least non-inferior to compounded TPN and provides nutritional intakes according to the new guidelines and provides the expected weight gain in preterm babies with a birth weight between 1250 and 2000g admitted in our NICU between 2015 & 2018

NCT ID: NCT04143204 Completed - Growth Clinical Trials

Nutrition and Growth in Very Preterm Infants

Start date: August 1, 2019
Phase:
Study type: Observational

This study aims to explore the relation of early nutritional intake, especially oral nutrition intake, with growth and body composition among very preterm or very low birth weight infants.

NCT ID: NCT04067973 Not yet recruiting - Premature Clinical Trials

Impact of Prematurity on the Optic Nerve

Start date: September 2, 2019
Phase:
Study type: Observational [Patient Registry]

The purpose of this protocol is to study the consequences of prematurity on the optic nerve. Indeed, the work already carried out on the subject suggests that prematurity induces suffering of the optic nerve with a loss of optical fibre, an essential element in the transmission of the visual nerve signal to the brain. The investigators will therefore study two populations: a population of premature infants aged 5 to 10 years, and a control population of term infants. The examinations performed are painless, non-invasive and non-irradiating. To date, there are no known adverse reactions to these tests. These examinations are a photo of the fundus (retinophotography), a pachymetry (measurement of the thickness of the non-contact cornea), an OCT RNFL (optical coherence tomography, scanner of the non-irradiating non-painful optical nerve) and the taking of the IOP (intraocular pressure). They aim to measure the main morphological characteristics of the eye and the optic nerve. This is a prospective observational study. The inclusion and measurements necessary for the study are made on the day of the consultation. The expected results will provide new data on this population of premature infants, allowing for better management if a pathology involving the optic nerve were to occur at any age in these patients.

NCT ID: NCT04041635 Recruiting - Premature Clinical Trials

Reduction of Visual and Auditory Stimuli to Reduce Pain During Venipuncture in Premature Infants.

VENOPUNCIPREM
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

The aim of the study is: To evaluate the efficacy of the reduction of visual and auditory stimuli on pain during venipuncture in premature newborns of 32-36 weeks of gestation.

NCT ID: NCT04035564 Completed - Hyponatremia Clinical Trials

Early Sodium Intake in Preterm Newborns

Start date: March 30, 2018
Phase: Phase 4
Study type: Interventional

Hyponatremia is a common complication among preterm infants, renal losses of sodium contribute to the development of hyponatremia in preterm newborns. Sodium imbalances impact in newborns outcome. There is controversy about the time of initiation and the requirements of sodium in premature infants. Hypothesis: early (24 hours of life) sodium supplementation (5mEq/kg/day) prevents the develop of hyponatremia in preterm infants.