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Clinical Trial Summary

This study is a multi-center, prospective, observational clinical trial study. 528 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1. In the cesarean section group, full term pregnant women with prelabor rupture of membrane (PROM) who are willing to try the trial of labor after cesarean (TOLAC) and in accordance with the criteria according to the 2016 China vaginal birth after cesarean (VBAC) clinical management guidelines will be enrolled and recorded by our homemade registration form of TOLAC. In the non-cesarean section group, pregnant women after 37 weeks of gestation with PROM but without vaginal labor contraindications will be enrolled. Whether in the cesarean section group or non-cesarean section group, if spontaneous labor does not occur, and they all will be induced by oxytocin. After 24 hours, their final delivery mode will be recorded. In the following 42 days postpartum, their complications and the neonatal outcome will be followed up.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT05333731
Study type Observational
Source The First Affiliated Hospital with Nanjing Medical University
Contact Jiang Ziyan, Ph.D
Phone 13512534017
Email zyjiangchm@163.com
Status Recruiting
Phase
Start date March 30, 2022
Completion date June 30, 2025

See also
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Completed NCT05215873 - Induction of Labor in Pregnant Women With Prelabor Rupture of Membranes - Oxytocin or Misoprostol Phase 4
Recruiting NCT04143685 - Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes N/A