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Nebivolol and the Endothelin (ET)-1 System — NETS  

Hypertension Clinical Trial

Official title:
Nebivolol and the Endothelin (ET)-1 System

Clinical Trial Summary

The investigators hypothesize that nebivolol will reduce ET-1-mediated vasoconstrictor tone in adult humans with elevated blood pressure to a greater extent than either metoprolol or placebo.

Clinical Trial Description

1. The investigators hypothesize that nebivolol will reduce ET-1-mediated vasoconstrictor tone in adult humans with elevated blood pressure to a greater extent than either metoprolol or placebo.

2. The investigators further hypothesize that reducing ET-1 vasoconstrictor activity contributes to the improvement in endothelial vasodilator function associated with nebivolol. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01395329
Study type Interventional
Source University of Colorado, Boulder
Contact
Status Completed
Phase Phase 4
Start date May 2011
Completion date December 2016
View Details
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