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Matrix Metalloproteinases's in Oral Biofluids During Pregnancy and Postpartum

Pregnancy Clinical Trial

Official title:
Modulation of Matrix Metalloproteinases-8, -9 and Endogenous Tissue Inhibitor-1 in Oral Biofluids During Pregnancy and Postpartum

Clinical Trial Summary

The aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of MMP-8, MMP-9 and TIMP-1 during 2/3 trimester of pregnancy and after delivery

Clinical Trial Description

MMP-8 and MMP-9 have been reported to reflect the inflammatory status in periodontal tissues and, therefore represent as potential biomarkers of periodontitis. The balance between tissue inhibitors of metalloproteinases (TIMPs) and MMPs play an important role in maintaining the integrity of healthy periodontium. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03516565
Study type Observational
Source Adnan Menderes University
Contact
Status Completed
Phase
Start date April 1, 2013
Completion date September 1, 2015
View Details
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