Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles

Pregnancy Clinical Trial

Official title:

Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles:Prospective Observational Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02942472
• Other study ID #: MOHEgypt
• Status: Not yet recruiting
• Phase: N/A
• First received: October 21, 2016
• Last updated: October 21, 2016
• Start date: October 2016
• Est. completion date: January 2017

Study information

• Verified date: October 2016
• Source: Ain Shams Maternity Hospital
• Contact: AMR H YEHIA, MD, MRCOG
• Phone: 0020127900014
• Email: am_helmy77[@]hotmail.com
• Is FDA regulated: No
• Health authority: Egypt: Ministry of Higher Education
• Study type: Observational

Clinical Trial Summary

Position of the tip of the inner catheter and air bubbles detection (at time,5min 10min)during embryo transfer influence the pregnancy rate in ICSI cycles .

Description:

The aim of this study is to assess the relationship between the position of the tip of the inner catheter, the position of the air bubbles (at time , 5 min ,10 min )after embryo transfer and pregnancy rate outcome in ICSI cycles. Most IVF teams consider not touching the endometrium and the uterine fundus with replacement of the embryos in the lumen of the endometrial cavity the most important factors for successful embryo transfer, it is highly recommended to use agents that can facilitate a smooth embryo transfer and reduce unintended stimulation of the fundus, for example the application of soft-tipped catheters, which can improve pregnancy rate.

The advantage of using the air and liquid content for catheter loading is to prevent the embryo from adhering to the wall of the catheter at the time of injection.The presence of two air bubbles on both sides of the medium that contains the embryo prevents the transfer of the embryo within the catheter and beside, in the transfer under ultrasonographic guidance, the air bubbles are often considered a marker for the embryo's position in the uterus.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 94
• Est. completion date: January 2017
• Est. primary completion date: January 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• BMI < 30 kg/ m2.

• Between 20 and 35years old.

• FSH levels on cycle day 3 of <12 mIU/mL.

• Both ovaries present deprived of morphological abnormalities and adequately visualized in Transvaginal ultrasound.

• Grade one or two embryo quality.

Exclusion Criteria:

• Hydrosalpinx.

• Intrauterine lesion.

• Patients undergoing ET after cryopreservation.

• Blood present on the catheter during the transfer procedure.

• A difficult transfer or with a suspicion of touching the fundus.

• Endometrial thickness less than 8mm.

• Known allergic reaction against one of the ingredient of the medications used during the study.

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Pregnancy

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams Maternity Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	clinical pregnancy rate		one and half year	Yes