Pregnancy Clinical Trial
Official title:
Comparing the Serum Vitamin D Levels and Pregnancy Rates in Women Undergoing Elective Frozen Embryo Transfer (eFET)
The aim of this study is determining the affects of serum vitamin D levels to implantation and clinical pregnancy rates in women undergoing elective vitrified/thawed embryo transfer. Two groups will be identified according to the serum vitamin D levels on eFET transfer day and later on implantation, clinical pregnancy and ongoing pregnancy rates will be compared between those groups
In the last decade there have been growing evidence about Vitamin D receptors and their role
in female genital tract. But these studies are yet not well designed and the results should
be interpreted cautiously. Although some of these studies advocating the Vitamin D
deficiency as an negative circumstance on pregnancy rates some of the others don't agree.
According to contradictory results understanding the actual role of those receptors needs
more observation.
Latest retrospective analyse postulated that, vitamin D deficiency in fresh single embryo
transfer cycles may reduce pregnancy rates mediated by endometrium or ovarian reserve and
stimulation characteristics.
For this reason the investigators aimed to explore the effect of serum Vitamin D levels on
pregnancy rates in infertile population undergoing frozen embryo transfer.
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