Pregnancy Clinical Trial
The purpose of this echocardiographic study is to restudy the longitudinal changes in
cardiac size and function during and after pregnancy in healthy women using relatively new
parameters of systolic and diastolic function as well as classical measures of left
ventricle (LV) function using contemporary echocardiographic machines.
We, the researchers at Hillel Yaffe Medical Center, will assess diastolic function and its
possible relation to shortness of breath.
A comprehensive echocardiographic study of the heart will be conducted in the first, second
and third trimesters of pregnancy and 3 months postpartum.
Determination of left ventricular dimensions, transvalvular Doppler flow, ejection fraction,
stroke volume, cardiac output, pulmonary vein flow, tissue Doppler, flow propagation, global
and segmental strain parameters, timing of peak strain and various parameters of diastolic
function will be obtained.
From these data normal values for various stages of pregnancy will be determined as well as
range for changes expected during longitudinal follow-up will be determined.
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Time Perspective: Prospective
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