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NCT00469807 Clinical Trial

Ghrelin Levels in Early IVF Pregnancies

Pregnancy Clinical Trial

Official title:
Maternal Serum Ghrelin Levels in Early IVF Pregnancies: Lack of Prognostic Value for Gestational Outcome and Altered Post-Prandial Responses

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00469807
Other study ID # VLC-CV-0604-507-22
Secondary ID
Status Completed
Phase N/A
First received May 3, 2007
Last updated April 27, 2017
Start date June 2004
Est. completion date May 2007

Study information
Verified date April 2017
Source Instituto Valenciano de Infertilidad, IVI VALENCIA
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In this study, we have assessed the potential prognostic value for gestational outcome of maternal ghrelin levels at very early stages of IVF pregnancies. In addition, ghrelin responses to meal intake were explored at early gestation.

Description:

Ghrelin is a pleiotropic hormone recently involved in the control of growth and metabolism, whose circulating levels fluctuate in relation to food intake and body mass index. Ghrelin has been detected in the decidualized endometrium, as well as in human and rat placenta, with a distinctive temporal pattern of expression along pregnancy.

Comparison(s): A total of 106 patients undergoing IVF procedures were prospectively recruited. On d-16 and 23 after oocyte retrieval, the patients were subjected to blood sampling after overnight fasting, for determination of serum ghrelin, hCG and progesterone levels. In addition, ghrelin levels were assayed in these groups, 2-h after ingestion of a fixed-calorie meal.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date May 2007
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 50 Years
Eligibility Inclusion Criteria:

- Patients undergoing IVF

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Spain Ivi Valencia Valencia

Sponsors (1)
Lead Sponsor Collaborator
Instituto Valenciano de Infertilidad, IVI VALENCIA

Country where clinical trial is conducted

Spain, 

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