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Pregnancy clinical trials

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NCT ID: NCT01674127 Completed - Clinical trials for Pregnant Women With Mild Preeclampsia

Effect of Methyldopa on Uterine Artery Diameter in Pregnant Women With Mild Preeclampsia

Start date: August 2011
Phase: Phase 2
Study type: Interventional

The present study examined the effects of Methyldopa on uterine artery diameter, uterine artery blood flow, umbilical artery and fetal middle-cerebral artery in patients with Preeclampsia, using Doppler ultrasound.

NCT ID: NCT01674114 Completed - Pregnancy Clinical Trials

Postoperative Morphine Consumption After Caesarean Section- TAP Block vs Intracutaneous Infiltration

Start date: September 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether a regional-block (TAP block) in Caesarean section will give a measurable benefit in form of reducing Morphine consumption as compared to local infiltration of the wound with local anesthetic.

NCT ID: NCT01672424 Completed - Pregnancy Clinical Trials

Ultrasound Assessment of Gastric Emptying

Start date: May 2012
Phase: N/A
Study type: Observational

Hypothesis: The volume of gastric contents will be the same for a high protein drink versus ice chips as measured by ultrasound at 20 minute intervals for two hours in the laboring parturient. Specific Aim: To determine the volume of gastric contents at various time intervals (every 20 minutes for 2 hours) in patients with an epidural that are given a high protein drink versus those that are given ice chips, with ultrasound.

NCT ID: NCT01669941 Completed - Pregnancy Clinical Trials

Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya

STOP MiP KENYA
Start date: August 2012
Phase: Phase 4
Study type: Interventional

Malaria in pregnancy (MiP) due to Plasmodium falciparum infection is a major cause of maternal morbidity and poor birth outcomes. Intermittent preventive treatment in pregnancy (IPTp) with Sulfadoxine pyrimethamine (SP), the administration of SP at predefined intervals in the second and third trimesters of pregnancy irrespective of the presence of malaria parasitemia, is currently recommended for HIV-negative women in all areas with stable moderate to high transmission of malaria. Due to increasing resistance to SP, it is no longer used as a treatment for symptomatic malaria, and the efficacy of IPTp-SP seems to be decreased. This study aims to look at a new drug, Dihydroartemisinin-Piperaquine (DP) for IPTp, as well as to explore the strategy of intermittent screening and treatment in pregnancy (ISTp) with DP. This strategy uses increased screening at time of focused antenatal care (FANC) with treatment of women who screen positive. The hypothesis is that the efficacy of both IPTp-DP and ISTp-DP will be associated with a reduction in malaria infection at delivery among HIV(-) women when compared to IPTp-SP, in an area with decreasing malaria transmission and high levels of SP resistance in Kenya.

NCT ID: NCT01668472 Withdrawn - Clinical trials for Pregnant Woman With Premature Rupture of Amnion Membranes

A Comparison of Rapid Immunoassay Tests for the Detection of Ruptured Membranes

Start date: August 2012
Phase: N/A
Study type: Observational

Specific objectives include analysis of performance of ROM Plus® in diagnosing ROM, as compared to Amnisure® and the conventional clinical assessment confirmed by a thorough chart review after delivery.

NCT ID: NCT01667978 Completed - HIV Clinical Trials

The Effect of Protease Inhibitors on the Pharmacokinetics of Oral Norethindrone Contraception

NET
Start date: June 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to learn if women taking the atazanavir and ritonavir have lower levels of a birth control medication called norethindrone. Norethindrone (also called the mini pill) is an FDA (Food and Drug Administration) approved progestin-only birth control pill used to prevent pregnancy. Norethindrone is the standard medication used in women who take the progestin only pill to prevent pregnancy. There are other birth control pills which contain different medications. The investigators want to learn if HIV medications (atazanavir and ritonavir) make the blood level of this birth control pill higher or lower. If the levels of norethindrone are too low it may not work to prevent pregnancy. The investigators also hope to learn about changes in the vaginal fluids and cervical fluids when women are taking this birth control pill.

NCT ID: NCT01666249 Suspended - Clinical trials for Pregnancy; Fetomaternal Hemorrhage

Clinical Efficacy of Postpartum Immunization of Rh and Coombs Negative Women With Sensitization Risk.

Start date: April 2014
Phase: Phase 3
Study type: Interventional

This a open, prospective, multicenter, single-arm, phase III study for clinical assessment of anti-Rh immunoglobulin (KamRho-D®) in Rh and Coombs negative women with risk sensitization. The anti-Rh immunoglobulin is an immunobiological containing high concentration of specific antibodies against factor D and "neutralizes" D antigen present in the Rh-positive fetal red blood cells (Rh +), which passed into the bloodstream of Rh-negative pregnant women (Rh).

NCT ID: NCT01664546 Not yet recruiting - Pregnancy Clinical Trials

Study of the Best Blastocyst Post Transfer by aCGH

Start date: September 2012
Phase: N/A
Study type: Observational

An Observational, blind and prospective study of Preimplantational Aneuploidy Screening by aCGH in Trophectoderm Biopsy

NCT ID: NCT01663350 Completed - Pregnancy Clinical Trials

Comparison of Aneuploidy Risk Evaluations

CARE
Start date: July 2012
Phase: N/A
Study type: Observational

This is a prospective, multiā€center observational study designed to compare the test results of the Verinata Health Prenatal Aneuploidy Test to results of conventional prenatal screening for fetal chromosome abnormalities in 'all-risk' pregnancies.

NCT ID: NCT01662596 Not yet recruiting - Pregnancy Clinical Trials

Detection of Risk Factors for Fetal Anomalies in a Rural Hospital Population

Start date: August 2012
Phase: N/A
Study type: Observational

The purpose of the study is to estimate the rate of risk factors for appearance of disease or fetal malformations in a population who turn to hospital "Hillel Yaffe" and examine whether there is a difference in the rate of early testing for diseases or birth defects in the fetus. Understanding the population and its risk factors, will allow specific reference to these risk factors to lowering them to eventually reduce the rate of congenital malformations in this population.