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Pregnancy clinical trials

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NCT ID: NCT02372422 Completed - Pregnancy Clinical Trials

Transvaginal Ultrasound Cervical Length Measurements in Twin Gestations

Start date: October 2002
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the use of routine transvaginal cervical length ultrasound can be used to prevent preterm deliveries in twin gestations.

NCT ID: NCT02372266 Completed - Pregnancy Clinical Trials

Safety and Cost-Effectiveness of Early Maternal Newborn Infant Discharge

Start date: April 1997
Phase: N/A
Study type: Interventional

To determine the effect of a policy of early maternal-newborn infant discharge (12-24 hours) with a home visit on admission to the Level II/III nursery and hospital admissions and readmissions.

NCT ID: NCT02365428 Completed - Pregnancy Clinical Trials

Evidence-based Websites to Increase Physical Activity for Pregnant Women

Start date: July 2014
Phase: N/A
Study type: Interventional

Fewer pregnant women achieve recommendations for physical activity (PA) (30 minutes of moderate PA 5 days of the week) as compared to non-pregnant women (15.8% to 26.1% respectively), and PA participation declines as pregnancy progresses. The benefits of PA during pregnancy are abundant to both the mother (e.g., reduced weight gain, lower risk of gestational diabetes) and the fetus (e.g., decreased fat mass, improved stress tolerance). Pregnancy represents a significant time in a woman's life in which she may be motivated to change her health behaviors due to concerns for the healthy development of the fetus and a quick return to pre-pregnancy weight. Hence, pregnancy represents a critical time to support women in PA participation. In our previous research, 94% of pregnant and postpartum women of varying socioeconomic statuses reported using the Internet for pregnancy and PA information. Despite some women increasing their PA participation as a result, most did not know if a website was reputable or reliable (i.e. evidence-based). Studies have reported that most online health information is unregulated and inaccurate. Further, women often receive inadequate PA information from physicians who are constrained by time and lack of knowledge about PA. Therefore, directing pregnant women to evidence-based websites via text messaging may provide a feasible approach to improve PA participation. PA participation in pregnant women is an ongoing challenge that warrants testing of innovative solutions. The purpose of this study is to determine the feasibility of using mobile phone text messaging to refer pregnant women to evidence-based websites for PA information to increase PA levels.

NCT ID: NCT02361710 Recruiting - Pregnancy Clinical Trials

Serum Vitamin D Levels and Pregnancy Rates in Women Undergoing Elective Frozen Embryo Transfer (eFET)

Start date: April 2015
Phase: N/A
Study type: Observational

The aim of this study is determining the affects of serum vitamin D levels to implantation and clinical pregnancy rates in women undergoing elective vitrified/thawed embryo transfer. Two groups will be identified according to the serum vitamin D levels on eFET transfer day and later on implantation, clinical pregnancy and ongoing pregnancy rates will be compared between those groups

NCT ID: NCT02351583 Withdrawn - Pregnancy Clinical Trials

Microcirculatory and Tissue and Cerebral Oxygenation in Preeclampsia and Normal Pregnancy: An Observation Study

Start date: January 1, 2015
Phase:
Study type: Observational

Preeclampsia is a disease of pregnancy affecting 3% to 8% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality. Characterized by alter placentation with subsequent release of inflammatory mediators leading to a generalized endothelial dysfunction. It is now accepted that endothelial dysfunction heralds the clinical manifestations of preeclampsia. The side-stream darkfield (SDF) microscopy device emits a 550 nm green light with a depth region of interest of 500 um. Green light is absorbed by the erythrocytes and appears black. SDF is a well-known non-invasive tool that can study the microcirculatory changes. It was used before in many situations especially in sepsis and septic shock patients. Near-infra-red spectroscopy (NIRS) device, measures the absorbance of near-infra-red (NIR) light by tissues perfused with oxygenated blood, and is capable of measuring changes in parenchymal volume tissues. It was used before in many situations (including pregnant patients) to reflect the tissue oxygenations. The investigators are planning to use the SDF and NIRS tools to study the microcirculatory change in preeclamptic subjects and normal pregnant subjects. If these two devices are able to determine any changes this should stand as a baseline for future studies in this field.

NCT ID: NCT02348840 Completed - Pregnancy Clinical Trials

Perinatal mHealth Intervention in Guatemala

Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of the study is to explore ways to improve maternal and child outcomes in the ethnic Maya speaking the Kaqchikel language population, which experiences wide disparities in health care access and outcomes when compared to other inhabitants of Guatemala who are not ethnically Maya and live in other parts of the country.

NCT ID: NCT02343848 Recruiting - Pregnancy Clinical Trials

Physical Activity and Gestational Complications

PEDPTB
Start date: July 2015
Phase: N/A
Study type: Interventional

The association between physical activity and several complication of pregnancy will be evaluated .

NCT ID: NCT02342002 Terminated - Pregnancy Clinical Trials

Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled Trial

Start date: January 2015
Phase: Phase 4
Study type: Interventional

The purpose of the proposed study is to compare - in a randomized, placebo-controlled, double-blinded trial - a combination of mifepristone and misoprostol to misoprostol used alone for missed abortion.

NCT ID: NCT02340442 Recruiting - Pregnancy Clinical Trials

DVA Risk Pregnancy

Start date: October 2013
Phase: N/A
Study type: Observational

Maternal obesity, overweight and hypertensive disorders are among the most important risk factors for complications during pregnancy. Several lines of evidence indicate that overweight or obese women, as well as women with hypertensive disorders show increased risks of preterm birth before 32 weeks. However, an easy to determine, common reliable prognostic factor which allows for the early identifications of risk patients is still lacking. Recently, it has been reported that assessment of endothelial function may be a new promising tool for predicting the risk of adverse pregnancy outcome. As such evidence has been provided that endothelial dysfunction is prevalent among women with preeclampsia and is able to identify women at increased risk of preterm delivery and small-for-gestational-age (SGA) births. Several lines of evidence indicate that functional and structural changes of retinal vessels are altered in vascular related disease and may predict cardio-vascular events. Consequently, the current study seeks to investigate whether flicker induced vasodilatation, a well established parameter to test vascular function in-vivo is altered in women with low and high risk pregnancies when compared to a healthy control group. The data gained from this study may provide the basis for a larger longitudinal trial to assess whether vascular changes in the retina may predict the risk for complication during pregnancy.

NCT ID: NCT02339389 Completed - Pregnancy Clinical Trials

Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?

matvent
Start date: August 14, 2014
Phase:
Study type: Observational

Epidural techniques offer the advantage of being able to titrate the level, density, and duration of the blockade through the use of a catheter and are associated with relative maternal hemodynamic stability. One of the disadvantages, however, include a raise in maternal temperature that is attributed to labor epidural technique. This study will assess if decreased maternal ventilation following induction of labor analgesia causes a raise in temperature.