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Pregnancy clinical trials

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NCT ID: NCT02474862 Completed - Pregnancy Clinical Trials

Healthy Expectations - A Program for Pregnant Women Experiencing Depressive Symptoms

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Start date: March 24, 2015
Phase: N/A
Study type: Interventional

This study is a randomized control trial (RCT) evaluating a Prenatal Walking Program (PWP) in comparison to a Postpartum Prep Program (PPP) comparison group for pregnant women experiencing depressive symptoms. In addition to assessing changes in depressive symptoms, the investigators will examine other key maternal outcomes (maternal functioning, pain, anxiety, stress, fatigue), as well as infant outcomes including birth record data (gestation, weight, Apgar scores, etc) and careful, in-person assessment of infant neurobiological functioning at 30 days postpartum.

NCT ID: NCT02473991 Recruiting - Pregnancy Clinical Trials

Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight

Start date: March 2015
Phase: N/A
Study type: Observational

The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.

NCT ID: NCT02472522 Completed - Pregnancy Clinical Trials

Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP Blocks

Start date: May 2015
Phase: N/A
Study type: Interventional

Comparative study of Ropivacaine and Ropivacaine with dexmedetomidine in transversus abdominis plane (TAP) block for post-operative analgesia in patients undergoing Caesarean Section.

NCT ID: NCT02471924 Completed - Pregnancy Clinical Trials

Predicting Hypotension Related to Spinal Anesthesia for Caesarean Section With Ultrasonography

Start date: June 17, 2015
Phase: N/A
Study type: Interventional

Spinal anesthesia is the main technique for caesarean section. This anesthesia is followed by a hypotension in 40% to 90% despite preventing tools. Hypotension is responsible of foetale and maternal suffering. It would be interesting to have a tool that could detect patient who are at risk to have hypotension.This study consist in measuring variations of under aortic velocity peak (ΔITVAo) which estimate the modification of the cardiac output by Trans thoraciq echography.

NCT ID: NCT02460185 Completed - Pregnancy Clinical Trials

Role of Maternal Physical Exercise on Spontaneous Labor Onset

Start date: May 2015
Phase: N/A
Study type: Interventional

Evaluate the effects of the practice of maternal physical exercise on the term of pregnancy as a method to enhance spontaneous labor.

NCT ID: NCT02457312 Completed - Pregnancy Clinical Trials

The Effect of 7 Days of Letrozole Pretreatment Combined With Misoprostol on the Placental and Decidual Tissues

Start date: March 2013
Phase: Phase 2
Study type: Interventional

The present study aims at studying the effect of letrozole in early pregnancy in placenta and decidua including the progesterone receptor and the apoptotic factors.

NCT ID: NCT02453230 Completed - Pregnancy Clinical Trials

The Effect of Light on the Fetal Biophysical Profile

Start date: January 2015
Phase: N/A
Study type: Interventional

Since the 1960's, perinatal mortality in the United States has been declining at a steady rate. This decline has thought to be the result of improved surveillance of normal and abnormal fetal behavior and using that information to determine those babies at risk for stillbirth. There are many tools available for surveillance. One of these tools, the bio-physical profile (BPP), incorporates a non-stress test (NST) with ultrasound assessment of fetal behavior . This test has been used for about the last 30 years with good safety and efficacy. The ultrasound evaluation includes monitoring fetal breathing, fetal gross and fine movement and amniotic fluid evaluation. NST and BPP have been found to have similar ability to predict fetal well-being, with similar safety and ease of performance. Several studies have observed the effect of sound as well as light on the NST and have found that it can shorten testing time without altering its ability to be interpreted properly or affecting fetal safety. However, similar studies have not been done with the BPP. Light stimulation has been proven to be safe for both the mother and the fetus with no harm having been demonstrated when used with NST.

NCT ID: NCT02451644 Recruiting - Pregnancy Clinical Trials

The Association Between Physical Activity and Pregnancy Rate Following Embryo Transfer

Start date: June 2015
Phase: N/A
Study type: Interventional

The study examines the association between the amount of physical activity of the patient, ie the number of steps daily / weekly, and the pregnancy rate after embryo transfer.

NCT ID: NCT02451332 Completed - Pregnancy Clinical Trials

Prenatal Inflammation and Perinatal Outcomes

Start date: October 2015
Phase: N/A
Study type: Interventional

Preventing poor perinatal outcomes is the goal of all prenatal care, yet just who will go on to develop preeclampsia or have a growth-restricted baby is notoriously difficult to predict. A growing body of evidence suggests inflammatory markers can help predict poor outcomes, even prior to, and beyond, the current pregnancy. Our project will measure the response of one robust inflammatory marker, C-reactive protein (CRP), to a safe immune provocation recommended for all pregnant women (the seasonal influenza vaccine), and to find out whether CRP response is associated with increased risk for gestational hypertension, preeclampsia, preterm delivery, or birth weight. This work will help inform whether inflammatory markers should become part of routine prenatal care.

NCT ID: NCT02451228 Completed - Pregnancy Clinical Trials

Indomethacin PK and PD Therapy in Pregnancy

Start date: May 2015
Phase:
Study type: Observational

This study will follow pregnant women who are taking indomethacin as Standard of Care (SOC) for the indications of preterm labor (PTL), short cervix, or other indications, to evaluate the pharmacokinetics (PK), what the body does to the drug, and pharmacodynamics (PD), effectiveness of the drug in treating the specific intended disease process of this medication. This will help us develop more information for medication dosing specific to pregnant women experiencing preterm labor. Indomethacin is often prescribed to pregnant women presenting with preterm labor or shortened cervix, which places them at risk for preterm labor and delivery. Indomethacin has been used since the 1970s to prolong pregnancy by decreasing uterine contractions. However, despite the widespread use of indomethacin in pregnancy, there is limited information available to help physicians determine how much indomethacin to prescribe and how often to prescribe it.