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Pregnancy clinical trials

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NCT ID: NCT06292195 Recruiting - Pregnancy Clinical Trials

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome

VitDTracking
Start date: November 3, 2023
Phase:
Study type: Observational [Patient Registry]

The VitDTracking study focuses on the relevance of maternal vitamin D levels and their association with prematurity, aiming to improve maternal and child health outcomes, particularly by reducing avoidable preterm births. In Portugal, vitamin D levels during pregnancy have never been studied. Epidemiological data from other countries reveal a high prevalence of vitamin D deficiency/insufficiency, especially in pregnant women. The hypovitaminoses prevalence remains high even with a supplementation dosage of 400 to 600 IU/day during pregnancy (dosage used in Portugal), which is considered as a suboptimal dose. This phenomenon is associated with adverse maternal and child outcomes, such as intrauterine growth restriction, preeclampsia, cholestasis, hypertension, and gestational diabetes as major causes of prematurity. Additionally, the Portuguese population has a higher prevalence of genome alterations that confer a lower capacity to produce vitamin D from sunlight exposure. These genetic characteristics are present in about 19% of the population, representing a prevalence four times higher than the European average (19% versus 4.75%), leading to a higher predisposition to vitamin D deficiency.

NCT ID: NCT06272591 Recruiting - Pregnancy Clinical Trials

Comparison of Patient Satisfaction With Home Induction and In-patient Induction.

Start date: November 20, 2023
Phase:
Study type: Observational

Induced labour is a medical intervention designed to initiate or accelerate the childbirth process when clinically indicated. Induced labour concerns 25.8% of pregnant women in France, according to the latest National Perinatal Survey 2021. This rate is rising steadily, since in 2016 induction concerned 22% of pregnancies. There are many medical indications for induction, both maternal and foetal. Induced labour in hospitals is beginning to reach its limits, given the reduction in the number of nursing staff and the reduction in the number of beds available. In some cases, patients are hospitalised for 24 to 72 hours before going into labour. In this context, the place where the birth takes place, whether at home or in hospital, is essential, with a potential impact on patient satisfaction and the experience of induction. Cervical ripening can be a difficult experience for women, with a feeling of loss of control at this crucial stage. The duration of induction is one of the factors that women would like to see changed when asked about the aftermath of induction. The option of inducing at home might seem to improve women's experience and reduce the length of their stay in hospital.

NCT ID: NCT06270056 Not yet recruiting - Pregnancy Clinical Trials

Evaluation of Telemedicine Medical Abortion Service in Ecuador

Start date: February 2024
Phase:
Study type: Observational

This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks pregnant.

NCT ID: NCT06264349 Not yet recruiting - Pregnancy Clinical Trials

Women and Maternity: Development of a Nutritional Education Project

MATER
Start date: March 15, 2024
Phase: N/A
Study type: Interventional

The "first 1000 days of life", from conception to 2 years of life, are crucial for promoting the health of both mother and baby. During this period, a woman's diet and lifestyle play a significant role in determining the future health of the child. The perinatal period is an ideal time for regular contact with healthcare providers who can institute an intervention to encourage pregnant women to make nutritional changes to improve their health and that of their babies. Therefore, an educational program on an appropriate lifestyle during the "first 1000 days" can represent a crucial primary prevention strategy in reducing the risk of developing obesity and non-communicable diseases (NCDs) during childhood and later adulthood.

NCT ID: NCT06261398 Recruiting - Pregnancy Clinical Trials

Better Birth Outcomes Through Technology, Education, and Reporting

BETTER
Start date: February 26, 2024
Phase: N/A
Study type: Interventional

This is a pragmatic randomized control trial to evaluate the BETTER intervention compared to standard obstetrical care (control) to determine whether it helps to reduce maternal anemia and other adverse pregnancy outcomes. The BETTER intervention includes one motivational interviewing session and bi-weekly text messages to encourage patients to connect with resources that address their social needs, including housing, food, and transportation. Quantitative data will be used to study participant outcomes, including surveys, and electronic health record data.

NCT ID: NCT06259097 Not yet recruiting - Pregnancy Clinical Trials

Different Medications to Induce Labor

Start date: May 2024
Phase: Phase 3
Study type: Interventional

This is a randomized controlled trial examining whether the use of misoprostol or pitocin, in combination with a foley catheter, is more effective at inducing labor in patients with a gravid BMI that is considered obese.

NCT ID: NCT06239701 Recruiting - Pregnancy Clinical Trials

Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use - RCT

Start date: January 22, 2024
Phase: N/A
Study type: Interventional

The overall goal of this pilot study is to develop and preliminarily evaluate an LPA intervention designed to reduce cannabis use during pregnancy.

NCT ID: NCT06233773 Not yet recruiting - Pregnancy Clinical Trials

The Effect of Kinesio Taping and Manual Lymph Drainage on Pregnant Women With Restless Legs Syndrome

Start date: March 2024
Phase: N/A
Study type: Interventional

Restless Leg Syndrome, a progressive and recurrent chronic sensorimotor disorder that creates an irresistible urge to move the legs and a feeling of discomfort, is seen in 15.4-26.0% of pregnant women in our country. Restless Leg Syndrome has negative effects on sleep, mood, cognitive health, daily activities and behavior in pregnant women; It can also cause preeclampsia, difficult labor, and cesarean delivery. Therefore, it is important for pregnant women with Restless Leg Syndrome to be treated appropriately. It is recommended that pregnant women use non-pharmacological treatments as they are not risky for fetal health. Kinesio taping and manual lymphatic drainage methods are used non-pharmacologically to support venous-lymphatic drainage and manage pain. These methods are economical, reliable and easy to apply. However, no study has been found in which Kinesio taping or manual lymphatic drainage was applied to a patient group with Restless Leg Syndrome during or outside pregnancy. The aim of this project is to determine the effect of Kinesio taping and manual lymphatic drainage on Restless Legs Syndrome severity, sleep quality and psychological well-being in pregnant women with Restless Legs Syndrome.

NCT ID: NCT06199154 Not yet recruiting - Pregnancy Clinical Trials

Induction of Labor in Morbidly Obese Patients

Start date: May 2024
Phase: Early Phase 1
Study type: Interventional

The goal of this randomized control trial is to compare different doses of Misoprostol (25 mcg vs 50 mcg) in induction of labor (IOL) in morbidly obese patients with BMI >40. It is known that morbid obesity is a risk factor for failed IOL and ultimately cesarean delivery (CD.) If the rates of vaginal delivery in this population can improve, then surgical morbidity can be reduced in these patients.

NCT ID: NCT06170905 Recruiting - Pregnancy Clinical Trials

Whey Protein Pre-load and Postprandial Glycemia in Pregnancy

ProGs
Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This pilot study aims to investigate the intake of whey protein prior to carbohydrate intake as an approach to modulate postprandial glucose excursions during pregnancy.