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Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial — 4P  

Pregnancy Induced Hypertension Clinical Trial

Official title:
Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia (4P) - a Randomised, Placebo-controlled, Double-blind Clinical Trial

Clinical Trial Summary

Hypertensive disorders of pregnancy (HDP) are with 50.000 deaths every year one of the major causes of maternal mortality worldwide, especially in low and middle income countries. This trial aims to determine whether a daily dose of combined low-dose aspirin, calcium, vitamin D3, folic acid and vitamin B12 in pregnancy reduces the incidence of pregnancy-induced hypertension in women at risk. Secondary and tertiary objectives include other maternal and neonatal outcomes.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02007837
Study type Interventional
Source UMC Utrecht
Contact Joyce L Browne, MD, MSc
Phone +31649650071
Email J.L.Browne@umcutrecht.nl
Status Not yet recruiting
Phase Phase 3
Start date January 2018
Completion date August 2018
View Details
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