Antibiotics for Postpartum Third and Fourth Degree Perineal Tear Repairs

Pregnancy Complications, Infectious Clinical Trial

Official title: A Randomized Controlled Trial of the Effect of Prophylactic Antibiotics on the Infection Rate in Postpartum Third and Fourth Degree Perineal Tear Repairs

Status Completed

Clinical Trial Summary

This study is undertaken to find out whether prophylactic antibiotics can decrease the infection rate in third and fourth degree perineal tear repairs done in the immediate postpartum period.

Clinical Trial Description

After obtaining consent patients who sustained third or fourth degree perineal laceration after vaginal delivery were randomly assigned to a single dose of antibiotic (cefotetan or cefoxitin, 1 g intravenously or clindamycin, 900 mg intravenously, if allergic to penicillin), or placebo (100ml normal saline) intravenously. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Pregnancy Complications
• Pregnancy Complications, Infectious

• NCT number: NCT00186082
• Study type: Interventional
• Source: Stanford University
• Status: Completed
• Phase: N/A
• Start date: September 2003
• Completion date: June 2008