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The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia — HUGS  

Preeclampsia Clinical Trial

Official title:
The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia: a Multicenter, Open-label, Single Arm Trial, Investigator Initiated Study

Clinical Trial Summary

This study is prospective, single arm group ,open label, and multicenter trial (with two parallel-group [Hydroxychloroquine 200mg with Aspirin 100mg or Aspirin 100mg])

Clinical Trial Description

This study is prospective, open label, and multicenter trial [Hydroxychloroquine 200mg with Aspirin 100mg] The study population consists of the singleton pregnancy at high risk for preeclampsia who had adverse pregnancy outcome (preeclampsia or fetal growth restriction or intrauterine fetal death) in previous pregnancy. After randomisation, participants are assigned to receive hydroxychloroquine 200mg with aspirin 100mg per day or aspirin 100mg per day. Treatment is initiated between 12 and 22 weeks' gestation and stopped at 36 weeks' gestation. The medication adherence to dosing should be maintained at more than 80%. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05287321
Study type Interventional
Source Chung-Ang University Hosptial, Chung-Ang University College of Medicine
Contact Yoo-min Kim, MD
Phone +82-2-6299-1661
Email yoominkim@cau.ac.kr
Status Recruiting
Phase Phase 3
Start date May 31, 2022
Completion date December 31, 2025
View Details
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