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Clinical Trial Summary

To investigate the metabolic effects of a low carbohydrate versus energy-matched standard diet in morbidly obese individuals with prediabetes awaiting bariatric surgery.


Clinical Trial Description

The metabolic benefits of calorie restriction in obese people with or without impaired glycaemia are well-established. The impact of diet composition, however, remains poorly understood. Hepatic lipid content strongly correlates with hepatic insulin resistance, which is a key feature of the pre-diabetic state. The investigators hypothesize that a low carbohydrate diet compared to an energy-matched standard diet in morbidly obese patients with prediabetes scheduled for bariatric surgery results in greater reduction in liver fat. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03880162
Study type Interventional
Source Insel Gruppe AG, University Hospital Bern
Contact
Status Active, not recruiting
Phase N/A
Start date May 13, 2019
Completion date August 2024

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