Prediabetes Clinical Trial
Official title:
Effect of Saxagliptin on Body Fat , Glucose and Beta Cell Function in Patients With Newly Diagnosed Pre-Diabetes Mellitus and Obesity
The purpose of the study is to examine the effect of Saxagliptin in the newly diagnosed people with pre-diabetes and obesity besides lifestyle intervention ,there to evaluate DPP 4 inhibitors of reversing pre-diabetes curative effect to normal blood sugar, and observe its influences on the targets of obesity related metabolic abnormalities, to explore new ways for intervention on populations with pre-diabetes and obesity .
Materials and Methods: This is a perspectiveness ,randomized, opening study, patients will
be randomly assigned to the standarddose Saxagliptin group ,the lifestyle intervention
group,the Metformin group and the low dose Saxagliptin group with a 6-month treatment
period.
Oral glucose tolerance test will examined before and 6 months post-treatment during the
trial.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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