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Clinical Trial Summary

NAC is the N-acetyl derivative of the naturally occurring amino acid, L-cysteine. It is a common over-the-counter supplement and also is available as an injectable pharmaceutical that protects the liver in cases of acetaminophen overdose. In the exercise physiology literature, both oral and injectable NAC have been shown to reduce fatigue and improve recovery from exertion which has interesting implications for exploring cancer-related fatigue.

In terms of cancer cell biology, reactive oxygen species (ROS) may play an important role in the development and progression of breast cancer


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT01878695
Study type Interventional
Source Thomas Jefferson University
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Status Completed
Phase Phase 1
Start date July 26, 2012
Completion date May 14, 2015