Pre-Eclampsia Clinical Trial
— MOM-HealthOfficial title:
Multi-Omics for Maternal Health After Preeclampsia
To develop strategies to identify postpartum women at risk for adverse cardiovascular outcomes and provide them with preventative therapies.
Status | Recruiting |
Enrollment | 1100 |
Est. completion date | December 2028 |
Est. primary completion date | December 2028 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 50 Years |
Eligibility | Inclusion Criteria: - Pregnant women 18 years of age to 50 years of age - 10-24 weeks gestation at time of enrollment - Singleton pregnancy - Planning to deliver at a study site (UCSD or VUMC) Exclusion Criteria: - Inability to give informed consent - Intrauterine fetal demise - Fetal genetic or structural anomaly - Institutionalization for psychiatric disorder, mental deficiency or incarcerated - Active or history of malignancy requiring major surgery or systemic chemotherapy - Multi-fetal gestation or a twin demise at any gestational age - Known maternal or fetal chromosomal anomalies - Patients who plan to keep their placenta after delivery |
Country | Name | City | State |
---|---|---|---|
United States | University of California, San Diego | San Diego | California |
Lead Sponsor | Collaborator |
---|---|
University of California, San Diego | National Human Genome Research Institute (NHGRI), Vanderbilt University Medical Center |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Other cardiovascular disease | 1st trimester - 13 months postpartum | ||
Primary | Preeclampsia | 2nd trimester - 13 months postpartum | ||
Primary | Gestational hypertension | 2nd trimester - Delivery | ||
Primary | Postpartum hypertension | Delivery - 13 months postpartum | ||
Secondary | Postpartum cardiovascular disease | Delivery - 13 months postpartum |
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