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Pre-Diabetic clinical trials

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NCT ID: NCT03508739 Suspended - Hypertension Clinical Trials

Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition

Start date: June 1, 2018
Phase: Phase 3
Study type: Interventional

Type 2 diabetes is common, increases in prevalence with age, and patients with diabetes have an increased risk of cardiovascular disease. A relatively new cardiovascular medication currently used for the treatment of heart failure in the United States inhibits an enzyme that breaks down a variety of signaling hormones. This clinical trial tests if it may also be a target for the treatment of diabetes by decreasing the breakdown of a hormone that increases insulin release after a meal.