Reducing Risk of Type 2 Diabetes: Hydroxychloroquine Use in Pre-Diabetes

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the short-term effects of the antimalarial medication, hydroxychloroquine (HCQ), compared with placebo using frequently sampled intravenous glucose tolerance testing (FSIGTT) methodology to study changes in insulin secretion and glucose tolerance in subjects at risk for developing Type 2 diabetes.

Clinical Trial Description

Diabetes is approaching epidemic proportions in the United States. This study evaluates the mechanisms of action of a generic drug that may have effects on glucose metabolism. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01326533
Study type	Interventional
Source	University of Pittsburgh
Contact
Status	Completed
Phase	Phase 4
Start date	March 2011
Completion date	December 2014

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