Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)

Status Active, not recruiting

Clinical Trial Summary

The investigators will test whether breathing through an inspiratory resistance device will improve the ability to be upright and decrease heart rate increases on standing in patients with postural tachycardia syndrome.

Clinical Trial Description

Chronic orthostatic intolerance, sometimes known as the postural tachycardia syndrome (POTS), is the most common disorder among patients seen at several centers specializing in diseases of the autonomic nervous system. It affects an estimated 500,000 people in the United States alone. POTS (excessive increase in heart rate [>30 min-1] on standing associated with orthostatic symptoms [including palpitation, chest pain syndrome, dyspnea on standing, mental clouding and difficulties with concentration], in the absence of orthostatic hypotension) can produce substantial disability among otherwise healthy people. Patients with POTS typically feel tired and run down. Many also report a myriad of symptoms that are hard to categorize, often involving fatigue. One study, from the Mayo Clinic, found that patients with POTS had a diminished quality of life when measured using a standard health status instrument (SF-36). In this pilot study, we will test the hypothesis that breathing through an inspiratory resistance device will improve orthostatic tolerance and reduce orthostatic tachycardia in patients with postural tachycardia syndrome. ;

Study Design

Related Conditions & MeSH terms

Postural Orthostatic Tachycardia Syndrome
Postural Tachycardia Syndrome
Syndrome
Tachycardia

Clinical Trial Details

NCT number	NCT00962728
Study type	Interventional
Source	Vanderbilt University Medical Center
Contact
Status	Active, not recruiting
Phase	N/A
Start date	July 2009
Completion date	December 2025

View Details

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