Clinical Trials Logo

Clinical Trial Summary

Most cases of infection of clean-contaminated wounds (wounds without gross spillage of organisms from the gastrointestinal tract) are thought to originate from the skin. Therefore, it is conceivable that application of an optimal antiseptic agent can reduce the rate of surgical wound infections. This trial is to compare the impact of disinfecting the skin with Chloraprep (2%chlorhexidine and 70% isopropyl alcohol) vs. Betadine on the rates of infection of clean-contaminated surgical wounds. The study will also assess the occurrence of adverse effects on the skin from either antiseptic agent and the cost-savings associated with the use of Chloraprep vs Betadine.


Clinical Trial Description

This is a prospective, randomized, multicenter clinical trial. All adult patients, who are scheduled for a clean-contaminated surgical procedure of the alimentary, respiratory, reproductive or urinary tract will be asked to participate. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention


Related Conditions & MeSH terms


NCT number NCT00290290
Study type Interventional
Source Baylor College of Medicine
Contact
Status Completed
Phase Phase 3
Start date September 2003
Completion date May 2008

See also
  Status Clinical Trial Phase
Not yet recruiting NCT01413659 - Evaluation of the Effect of Preoperative Symbiotic Bowel Conditioning on Surgical Site Infection After Elective Colorectal Surgery Phase 0
Completed NCT00287599 - Rapid Identification of Key Pathogens in Wound Infection by Molecular Means N/A
Completed NCT03574090 - Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Colorectal Surgery Phase 4
Completed NCT01212315 - Effects of Triclosan-coated Sutures in Cardiac Surgery Phase 4
Completed NCT03174223 - Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates
Withdrawn NCT01691352 - Wick vs. No Wick: Does Method of Closure Affect Rate of Wound Infection? N/A
Completed NCT01089712 - Management Practices and the Risk of Infection Following Cardiac Surgery N/A
Completed NCT00987402 - Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation Phase 1/Phase 2
Completed NCT00484055 - Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery N/A
Completed NCT04088162 - The Use of Post-operative NPWT Dressing in the Prevention of Infectious Complications After Ostomy Reversal Surgery N/A
Recruiting NCT04725916 - Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study) N/A
Completed NCT00906074 - Study Evaluating Severe Surgical Site Infections (SSIs) Following Contaminated Or Dirty-infected Abdominal Surgery N/A
Not yet recruiting NCT01184430 - Effect of Perioperative Hemodynamic Optimization on the Immune Function Parameters of Peripheral Blood Monocytes After Cardiac Surgery N/A