Continuous Ultrasound Guided Erector Spinae Plane Block vs Thoracic Paravertebral Block

Postoperative Pain Clinical Trial

Official title:

Continuous Ultrasound Guided Erector Spinae Plane Block vs Thoracic Paravertebral Block for Postoperative Analgesia in Patients Undergoing Thoractomy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05898607
• Other study ID #: 2/2023ANET10-25
• Status: Completed
• Phase: N/A
• Start date: February 10, 2023
• Est. completion date: January 25, 2024

Study information

• Verified date: January 2024
• Source: Menoufia University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

in this study the investigators will investigate and compare the analgesic efficacy of two techniques (continuous TPVB and continuous ESPB) in relieving thoracotomy pain

Description:

General Anesthesia will be induced with Fentanyl (1-2 μg/kg), Propofol (2-3 mg/kg), and Atracurium (0.5-0.8 mg/kg). Pressure controlled Volume guarantee Ventilation mode will be used to maintain O2 Saturation Above 98% and End tidal co2 Around 30-35 mmHg. Anesthesia will be maintained with Isoflurane 1.2 Minimum Alveolar Concentration inhalation after induction Group A: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous infusion U/S-Guided TPVB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative and Group B: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous U/S-Guided ESPB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: January 25, 2024
• Est. primary completion date: October 10, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 21 Years and older

Eligibility

Inclusion Criteria:

• Eligible 40 patients will be older than 21 years old with American society of anesthesia physical status I& II scheduled for elective thoracotomy

Exclusion Criteria:

• Patients who are:

• Uncooperative.

• Having allergy to any of the study drugs.

• Known abuse of alcohol or medication.

• Having Local infection at the site of injection or systemic infection.

• Pregnancy.

• With coagulation disorders or on anticoagulation therapy

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain

Intervention

Other:
• continuous Thoracic paravertebral block
continuous infusion U/S-Guided TPVB of 5 ml/hr of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative.
• continuous Erector spinae plane block
continuous U/S-Guided ESPB of 5 ml/hr of 0.125% bupivacaine started through the catheter before the surgical procedure

Locations

Country	Name	City	State
Egypt	Menoufia university	Cairo	Shibin Elkom

Sponsors (4)

Lead Sponsor	Collaborator
Amal Gouda Elsayed Safan	Mohamed Emad Basune, Rabab Mohammed Habeeb, Wesam Eldin Sultan

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Compare the VAS score postoperative of (U/S)-guided continuous (ESPB) to continuous (TPVB) following thoracotomy	visual analogue scale (VAS) Score	48 hours
Secondary	1 st call analgesia	mg	1 hour
Secondary	Total rescue opioid dose used	mg	48 hour
Secondary	patient satisfaction at 24 hours		24 hours
Secondary	occurrence of adverse events		24hours
Secondary	hospital stay	days	1 week