Vitamin D Levels and Postoperative Pain in Laparoscopic Cholecystectomy

Postoperative Pain Clinical Trial

Official title:

Effect of Vitamin D Levels on Postoperative Pain and Narcotic Analgesia in Patients With Laparoscopic Cholecystectomy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04687527
• Other study ID #: 189_2020.03.25_02
• Status: Completed
• Start date: May 15, 2020
• Est. completion date: April 30, 2021

Study information

• Verified date: June 2021
• Source: Bozok University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The deficiency of vitamin D is common in patients with gastrointestinal system disorders.

Vitamin D has been associated with chronic non-specific musculoskeletal pain and migraines due to anti-inflammatory effects.

This prospective observational study will undergo elective laparoscopic cholecystectomy surgery between 18 and 65 years, is planned to participate in ASA (American Society of Anesthesiologists) 1-3, 90 volunteer patients.

In preoperative evaluation, the remaining 3 ml of blood was centrifuged from the routine received blood to determine the level of vitamin D will be kept.

Postoperative will be applied to patient controlled analgesia to all patients for 24 hours.

To determine the level of postoperative pain, the visual analog scale (VAS) will be used in the clock unit and at the service 6, 12 and 24 hours.

In this study, the investigators aimed to test the hypothesis of relation to pain and opioid consumption in acute postoperative (24 hours) of perioperative low-vitamin D.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: April 30, 2021
• Est. primary completion date: April 15, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Volunteer,

• Between the Ages Of 18-65,

• Least Primary School Graduate,

• Not Using Drugs That May Affect Cognitive Functions,

• Non-Alcohol Substance Use,

• Patients Without Psychiatric and Neurological Disease.

Exclusion Criteria:

• Those with known psychiatric disease and drugs,

• Those with an important cardiovascular or central nervous system disease,

• Patients with pain syndromes or routinely using opioid.

Very urgent patients

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain
• Vitamin D Deficiency

Locations

Country	Name	City	State
Turkey	Bozok University Medical Center	Yozgat

Sponsors (1)

Lead Sponsor	Collaborator
Bozok University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	preoperative Vitamin D Level and postoperative pain in patients to undergo laparoscopic cholecystectomy operation	Correlations of preoperative Vitamin D Level between postoperative pain in patients undergoing laparoscopic cholecystectomy.to undergo laparoscopic cholecystectomy operation	6 months
Secondary	preoperative Vitamin D Level and opioid analgesic consumption	Correlations of preoperative Vitamin D Level between opioid analgesic consumption in patients undergoing laparoscopic cholecystectomy.to undergo laparoscopic cholecystectomy operation	6 months