Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy

Postoperative Pain Clinical Trial

Official title:

Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03288428
• Other study ID #: NABUMORPHINE
• Status: Recruiting
• Phase: Phase 4
• First received: June 11, 2017
• Last updated: November 1, 2017
• Start date: May 1, 2017
• Est. completion date: December 31, 2018

Study information

• Verified date: November 2017
• Source: Peking University First Hospital
• Contact: Yan Zhou, MD
• Phone: 13641202040
• Email: zhouyanlion[@]163.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

to compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy.

Description:

To compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy, by using patient controlled analgesia postoperatively, a randomized, double blind clinical trial. Patients undergoing elective Laparoscopic myomectomy are randomly divided into two groups: nalbuphine and morphine groups. All patients are under general anesthesia with routine methods. The nalbuphine group receive postoperative patient controlled analgesia using nalbuphine 30mg/120ml, while the morphine group receive postoperative patient controlled analgesia using morphine 60mg/120ml. Perioperative parameters are to be collected to compare the two groups.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 80
• Est. completion date: December 31, 2018
• Est. primary completion date: December 31, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• elective Laparoscopic myomectomy patients 24hr post-operative patient controlled analgesia analgesia no mild or severe liver or renal disfunction

Exclusion Criteria:

• can't understand patient controlled analgesia device refuse trial

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain

Intervention

Drug:
• Nalbuphine
patient controlled analgesia with Nalbuphine
• Morphine
patient controlled analgesia with Morphine

Locations

Country	Name	City	State
China	First hospital Peking University	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking University First Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	numerical rating scale	1-10	24 hr post-operatively