Efficacy of Buprenorphine on Postoperative Endodontic Analgesia

Postoperative Pain Clinical Trial

— EBPEA  

Official title:

Efficacy of Buprenorphine on Postoperative Endodontic Analgesia

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT03268278
• Other study ID #: UHClevelandMCBupStudy
• Status: Terminated
• Phase: Phase 1
• Start date: April 1, 2017
• Est. completion date: July 1, 2018

Study information

• Verified date: April 2019
• Source: University Hospitals Cleveland Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To see whether the addition of buprenorphone to local anesthesia will lengthen postoperative analgesia for endodontic pain

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 10
• Est. completion date: July 1, 2018
• Est. primary completion date: July 1, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• persons with preoperative pain to percussion of a tooth with pulpal disease requiring endodontic therapy, healthy individuals, ASA Class I and II, no known allergies to the drugs being administered

Exclusion Criteria:

• pregnancy, allergy to buprenorphine, allergy to local anesthetic

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain

Intervention

Drug:
• Buprenorphine
Buprenorphine plus local anesthetic
• Sterile saline
Placebo 1,8 ml
• lidocaine, epinephrine (Local anesthetic)
2% lidocaine 1:100,000 epinephrine

Locations

Country	Name	City	State
United States	University Hospitals Cleveland Medical Center	Cleveland	Ohio

Sponsors (1)

Lead Sponsor	Collaborator
University Hospitals Cleveland Medical Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The Efficacy of Buprenorphine in addition to Local Anesthetic in Providing Prolonged Postoperative Endodontic Analgesia	The number of patients with extended postoperative analgesia when compared to the baseline in pain scores on a visual analog scale during a three-day period will be analyzed. A questionnaire containing a visual analog scale and a log for recording the use of rescue analgesics will be used to gather the data.	two years